Rani 150 mg (Tablet)
Unit Price: ৳ 2.01 (10 x 10: ৳ 201.00)
Strip Price: ৳ 20.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Alco pharma ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage
- Recurrent haemorrhage in patients
- Before general anesthesia in at-risk patients
Pharmacology
- Competitively blocks histamine at H2-receptors
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
Dosage & Administration
- 150 mg twice daily for duodenal and gastric ulcer
- 300 mg as a single daily dose at night for 4 to 8 weeks
- 150 mg twice daily for reflux oesophagitis
- 150 mg 3 times daily for Zollinger Ellison syndrome
- 150 mg twice daily for episodic dyspepsia
- 150 mg at night for preventing recurrences
- 2-4 mg/kg twice daily for children with peptic ulcer
- Slow intravenous injection of 50 mg for prophylaxis of haemorrhage
- Intravenous infusion at a rate of 25 mg per hour for prophylaxis
- Intramuscular injection of 50 mg every six to eight hours for prophylaxis
- Oral dose of 2 mg/kg to 4 mg/kg for children with peptic ulcer
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Excreted in human breast milk
Precautions & Warnings
- Reduced dosage in patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy recommended
- Haemodiaiysis may be required
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Various dilution concentrations for different modes of administration
Storage Conditions
- Store in a cool and dry place
- Protect from light