Ranicare 150 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Novelta bestway pharma ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration
- Reflux oesophagitis
- Episodic dyspepsia
Pharmacology
Competitively blocks histamine at H2-receptors, inhibits gastric acid secretion, does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion, or serum gastrin
Dosage & Administration
- Usual dosage of 150 mg twice daily for active duodenal and benign gastric ulcers
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- 300 mg as a single daily dose at night for 4 to 8 weeks
- Reflux oesophagitis: 150 mg twice daily or 300 mg at bedtime for up to 8 weeks
- Zollinger-Ellison syndrome: 150 mg 3 times daily and increased if necessary
- Episodic dyspepsia: 150 mg twice daily or 300 mg at bedtime for up to 6 weeks
- Maintenance: 150 mg at night for preventing recurrences
- Ranitidine injection may be given intravenously or intramuscularly at specified doses
- Recommended oral dose for children for the treatment of peptic ulcer
- Safety and effectiveness of Ranitidine injection have not been established in case of children
Interaction
Delayed absorption and increased peak serum concentration with propantheline bromide, minimally inhibits hepatic metabolism of certain drugs, may alter absorption of pH-dependent drugs, may reduce bioavailability with antacids
Contraindications
Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
Ranitidine crosses the placenta, caution should be exercised when administered to a nursing mother
Precautions & Warnings
Should be given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
Ulcer healing rates have been found similar in elderly patients, no difference in the incidence of adverse effects
Overdose Effects
No particular problems are expected following overdosage, symptomatic and supportive therapy should be given as appropriate
Therapeutic Class
H2 receptor antagonist
Reconstitution
- Ranitidine 50 mg diluted to specified concentrations with different injectable solutions
- Recommendations for patients with Zollinger-Ellison syndrome or other hypersecretory conditions
Storage Conditions
Store in a cool and dry place, protect from light