Ranison 150 mg (Tablet)

Unit Price: ৳ 1.73 (10 x 10: ৳ 173.00)

Strip Price: ৳ 17.30

Medicine Details

Category	Details
Generic	Ranitidine hydrochloride
Company	Jayson pharmaceuticals ltd
Also available as	Ranison 50 mg injection

Indications

Treatment of active duodenal ulcer
Benign gastric ulcer
Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
Post operative stress ulcer
Zollinger-Ellison Syndrome
Gastroesophageal reflux disease (GERD)
Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
Recurrent haemorrhage in patients with bleeding peptic ulcer
Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients

Pharmacology

Competitively blocks histamine at H2-receptors of the gastric parietal cells which inhibits gastric acid secretion.

Dosage & Administration

Usual dosage: 150 mg twice daily or 300 mg as a single daily dose at night for 4 to 8 weeks
Children's dosage: 2-4 mg/kg twice daily, maximum 300 mg daily
Dosage for Zollinger Ellison syndrome: 150 mg 3 times daily and increased if necessary up to 6 g daily in divided doses
Dosage for episodic dyspepsia: 150 mg twice daily or 300 mg at bedtime for up to 6 weeks
Maintenance dosage: 150 mg at night for preventing recurrences

Interaction

Delayed absorption and increased peak serum concentration with propantheline bromide. May alter absorption of pH-dependent drugs. May reduce bioavailability with antacids.

Contraindications

Patients hypersensitive to Ranitidine

Side Effects

Altered bowel habit
Dizziness
Rash
Tiredness
Reversible confusional states
Headache
Decreased blood counts
Muscle or joint pain

Pregnancy & Lactation

Ranitidine crosses the placenta
Caution should be exercised when administered to a nursing mother

Precautions & Warnings

Should be given in reduced dosage to patients with impaired renal and hepatic function

Use in Special Populations

Ulcer healing rates in elderly patients similar to those in younger patients

Overdose Effects

Specific in action; symptomatic and supportive therapy should be given as appropriate

Therapeutic Class

H2 receptor antagonist

Reconstitution

Ranitidine 50 mg diluted to a concentration ≤2.5 mg/mL for slow IV injection
Ranitidine 50 mg diluted to a concentration ≤0.5 mg/mL for intermittent slow IV infusion
Ranitidine 150 mg diluted in 250 mL of dextrose 5% inj or NaCl 0.9% for continuous IV infusion

Storage Conditions

Store in a cool and dry place, protect from light