Ranitab 150 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Sonear laboratories ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal hemorrhage from stress ulcer
- Recurrent hemorrhage in patients with bleeding peptic ulcer
- Preventive treatment before general anesthesia
Pharmacology
Competitively blocks histamine at H2-receptors of the gastric parietal cells, inhibits gastric acid secretion, does not affect pepsin secretion, pentagastrin-stimulated intrinsic factor secretion or serum gastrin
Dosage & Administration
- Dosage for duodenal and gastric ulcer
- Dosage for reflux oesophagitis
- Dosage for Zollinger Ellison syndrome
- Dosage for episodic dyspepsia
- Maintenance dosage
- Child dosage for peptic ulcer
- Ranitidine IV injection and IV infusion dosage
- Dosage for pediatric use
Interaction
Delayed absorption and increased peak serum concentration with propantheline bromide, minimal inhibition of hepatic metabolism of certain drugs, alteration of absorption of pH-dependent drugs, reduction of bioavailability with antacids
Contraindications
Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Excreted in human breast milk
Precautions & Warnings
Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
Use in elderly patients
Overdose Effects
Specific in action, symptomatic and supportive therapy, possible removal from plasma by hemodialysis
Therapeutic Class
H2 receptor antagonist
Reconstitution
Reconstitution instructions for different types of intravenous administration
Storage Conditions
Store in a cool and dry place, protect from light