Ranitid 75 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal hemorrhage from stress ulcer
- Recurrent hemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in at-risk patients
Pharmacology
Competitively blocks histamine at H2-receptors, inhibiting gastric acid secretion
Dosage & Administration
- Tablet & Syrup:
- Duodenal and gastric ulcer: 150 mg twice daily for 4-8 weeks
- Reflux oesophagitis: 150 mg twice daily for up to 8 weeks
- Zollinger Ellison syndrome: 150 mg 3 times daily; maximum 6 g daily
- Episodic dyspepsia: 150 mg twice daily for up to 6 weeks
- Maintenance: 150 mg at night for prevention
- Child (peptic ulcer): 2-4 mg/kg twice daily; max 300 mg daily
- IV injection & IV Infusion: Dosage varies based on specific condition and patient age
Interaction
Delayed absorption and increased peak serum concentration with propantheline bromide. Minimal inhibition of hepatic metabolism of certain drugs and alteration of pH-dependent drug absorption. May reduce bioavailability with antacids
Contraindications
Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Pregnancy: Should only be used if considered essential
- Lactation: Caution should be exercised
Precautions & Warnings
Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
Similar healing rates in elderly patients as in younger patients, with no significant difference in adverse effects
Overdose Effects
No particular problems expected. Symptomatic and supportive therapy should be given as appropriate
Therapeutic Class
H2 receptor antagonist
Reconstitution
Specific dilution instructions for different administration routes and conditions
Storage Conditions
Store in a cool and dry place, protect from light