Vigosol 5% (IV Infusion)

500 ml bottle: ৳ 352.00

Medicine Details

Indications

  • Intravenous nutrition
  • Protein synthesis
  • Surgery recovery
  • Burns
  • Renal insufficiency
  • Hepatic insufficiency
  • Cancer management

Composition

  • Essential Amino Acids:
    • L-Isoleucine
    • L-Leucine
    • L-Lysine Hydrochloride
    • L-Methionine
    • L-Phenylalanine
    • L-Threonine
    • L-Tryptophan
    • L-Valine
    • L-Histidine
    • L-Tyrosine
  • Non Essential Amino Acids:
    • L-Arginine
    • L-Aspartic Acid
    • L-Glutamic Acid
    • L-Alanine
    • L-Cystine
    • Glycine (Aminoacetic Acid)
    • L-Proline
    • L-Serine
  • Excipients:
    • D-Sorbitol
  • Electrolytes:
    • Sodium (Na+)
    • Potassium (K+)
    • Magnesium (Mg++)
    • Chloride (Cl-)
    • Acetate (CH3COO-)
  • Total Nitrogen Content: 7.25 gm/L
  • Total Energy Content: 1551 kj/L (371.14 Kcal/L)

Pharmacology

  • Sterile aqueous solution
  • Necessary for parenteral nutrition
  • Contains essential and non-essential amino acids
  • Clear and colorless to pale yellow
  • pH range 5.0 to 7.0

Dosage & Administration

  • Dependent on patient's condition and metabolic stress
  • Slow infusion rates
  • Different dosage for obese patients
  • Specific rate of infusion for children and infants

Interaction

No expected interactions at recommended dosage

Contraindications

  • Inborn errors of amino acids metabolism
  • Severe liver dysfunction
  • Severe uremia without dialysis facilities
  • Hyperosmolar nonketotic diabetic coma

Side Effects

  • Rarely nausea
  • Potential vomiting, flushing, and sweating at high infusion rates
  • Transient liver test increases
  • Hypersensitivity reactions
  • Thrombophlebitis risk
  • Potential hyperphenylalaninemia in premature infants

Pregnancy & Lactation

Reported safe in humans, no animal reproduction studies

Precautions & Warnings

  • Increased urinary excretion of trace elements
  • Risk of hyperphenylalaninemia in premature infants
  • Caution in diabetes, severe heart failure, and renal impairment
  • Need for monitoring in malnourished patients
  • Potential thiamine deficiency syndrome
  • Recommendations for serum potassium and blood glucose monitoring

Overdose Effects

  • Nausea, vomiting, sweating
  • Thrombophlebitis
  • Osmotic diuresis with dehydration
  • Symptoms related to hyperglycemia

Therapeutic Class

Parenteral nutritional preparations

Storage Conditions

Protect from light, store between 15°C to 25°C, avoid freezing, keep out of reach of children

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