Ranix 50 mg/2 ml (IM/IV Injection)
2 ml ampoule: ৳ 6.00 (2 x 5: ৳ 60.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Chemist laboratories ltd |
Title
- Ranix Tablet
- Ranix Syrup
- Ranitidine Tablet
Categories
- Gastrointestinal Medication
- Ulcer Treatment
- Reflux Medication
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particulary obstetric patients
Pharmacology
- Competitively blocks histamine at H2-receptors of the gastric parietal cells
- Inhibits gastric acid secretion
- Does not affect pepsin secretion
- Pentagastrin-stimulated intrinsic factor secretion or serum gastrin
Dosage & Administration
- Dosage for duodenal and gastric ulcer
- Dosage for reflux oesophagitis
- Dosage for Zollinger Ellison syndrome
- Dosage for episodic dyspepsia
- Maintenance dosage
- Dosage for children with peptic ulcer
- Ranitidine IV injection & IV Infusion dosage
- Dosage for prophylaxis of haemorrhage from stress ulceration
- Dosage for prophylaxis of upper gastrointestinal haemorrhage from stress ulceration
- Dosage for patients at risk of developing aspiration syndrome
- Recommended oral dose for the treatment of peptic ulcer in children
- Safety and effectiveness of Ranitidine injection in children
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of coumarin anticoagulants, theophylline, diazepam and propanolol
- May alter absorption of pH-dependent drugs (e.g. ketoconazole, midazolam, glipizide)
- May reduce bioavailability with antacids
Contraindications
- Patients hypersensitive to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the foetus
- Caution when administered to a nursing mother
Precautions & Warnings
- Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Use in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy should be given as appropriate
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Guidelines for slow IV injection, intermittent slow IV infusion, continuous IV infusion
- Dilution recommendations for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light