Acudipin 5 mg (Tablet)

Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)
Strip Price: ৳ 50.20

Medicine Details

Indications

  • Essential hypertension
  • Angina pectoris
  • Vasospastic angina

Pharmacology

  • Dihydropyridine calcium-channel blocker
  • Long duration of action
  • Influences myocardial cells
  • Vasodilation
  • Reduced peripheral resistance
  • Increased coronary blood flow

Dosage & Administration

  • Usual dose is 5 mg once daily for hypertension
  • Maximum dose is 10 mg once daily
  • Lower dose for elderly and patients with hepatic insufficiency

Interaction

  • Potentially hazardous interactions with p-blockers
  • Absence of interaction with Digoxin
  • Absence of interaction with Cimetidine
  • No significant alteration with Warfarin
  • Food does not alter absorption

Contraindications

  • Hypersensitivity to dihydropyridine derivatives
  • Pregnancy

Side Effects

  • Dizziness
  • Flushing
  • Headache
  • Hypotension
  • Peripheral edema

Pregnancy & Lactation

  • Pregnancy Category C
  • Recommended to discontinue nursing

Precautions & Warnings

  • Caution in hepatic impairment
  • Caution during pregnancy and breastfeeding

Use in Special Populations

  • 2.5 mg once daily for children with hypertension (6-17 years)
  • Effect on blood pressure in children under 6 years not known
  • Normal dosage recommended for elderly
  • Normal dosage recommended for renal impairment
  • Caution in dosage selection for hepatic impairment

Overdose Effects

  • Excessive peripheral vasodilatation
  • Reflex tachycardia
  • Marked systemic hypotension
  • Recommendations for clinical management

Therapeutic Class

  • Calcium-channel blockers

Storage Conditions

  • Store in a cool & dry place, protected from light

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