Acudipin 5 mg (Tablet)
Unit Price: ৳ 5.02 (5 x 10: ৳ 251.00)
Strip Price: ৳ 50.20
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate |
Company | Concord pharmaceuticals ltd |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose is 5 mg once daily for hypertension
- Maximum dose is 10 mg once daily
- Lower dose for elderly and patients with hepatic insufficiency
Interaction
- Potentially hazardous interactions with p-blockers
- Absence of interaction with Digoxin
- Absence of interaction with Cimetidine
- No significant alteration with Warfarin
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
Pregnancy & Lactation
- Pregnancy Category C
- Recommended to discontinue nursing
Precautions & Warnings
- Caution in hepatic impairment
- Caution during pregnancy and breastfeeding
Use in Special Populations
- 2.5 mg once daily for children with hypertension (6-17 years)
- Effect on blood pressure in children under 6 years not known
- Normal dosage recommended for elderly
- Normal dosage recommended for renal impairment
- Caution in dosage selection for hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Recommendations for clinical management
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store in a cool & dry place, protected from light