Amlotab 10 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
- Monotherapy
- Combination therapy
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
Dosage & Administration
- Usual dose: 5 mg once daily
- Maximum dose: 10 mg once daily
- Lower dose for elderly and patients with hepatic insufficiency
- May be taken without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect
- Food does not alter absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Paradoxical increase in ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Should be used during pregnancy only if benefit justifies risk
- Not known excretion in human milk
- Recommendation to discontinue nursing
Precautions & Warnings
- Caution in patients with hepatic impairment
- Caution during pregnancy and breastfeeding
Use in Special Populations
- Dosing for children with hypertension
- Effect in children under 6 years old unknown
- Elderly tolerance
- Normal dosage recommended in renal impairment
- Dose selection caution in mild to moderate hepatic impairment
- Initiate at lowest dose in severe hepatic impairment
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Marked systemic hypotension
- Potentially fatal shock
- Active cardiovascular support required
- Gastric lavage may be worthwhile
- Use of charcoal to reduce absorption rate
- Dialysis unlikely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light