Dipicard 5 mg (Tablet)
Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of essential hypertension as monotherapy
- Treatment of angina pectoris as monotherapy
- Treatment of vasospastic angina
- May be used in combination with other antihypertensive or antianginal agents
Pharmacology
- Dihydropyridine calcium-channel blocker
- Long duration of action
- Influences myocardial cells and vascular smooth muscle
- Results in vasodilation and reduced peripheral resistance
- Increased coronary blood flow and myocardial oxygen supply
Dosage & Administration
- Usual dose of 5mg once daily for hypertension
- Maximum dose of 10mg once daily for hypertension
- Lower starting dose for elderly or hepatically impaired patients
- Dosage of 5-10mg for angina (chronic stable or vasospastic)
Interaction
- Potential hazardous interactions with p-blockers in severely impaired cardiac patients
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect
- No influence of food on absorption
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Contraindicated in pregnant women
Side Effects
- Common adverse effects include dizziness, flushing, headache, hypotension, peripheral edema
- Gastrointestinal disturbances, increased micturition frequency, lethargy
- Paradoxical increase in ischaemic chest pain
- Rashes, fever, abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if benefits outweigh risks
- Unknown excretion in human milk
- Discontinue nursing while on Amlodipine
Precautions & Warnings
- Risk in patients with hepatic impairment, pregnancy, and breastfeeding
Use in Special Populations
- Varied dosages for children and elderly
- Considerations for renal and hepatic impairment
Overdose Effects
- Symptoms of excessive peripheral vasodilatation and hypotension
- Management with cardiovascular support, vasoconstrictors, calcium gluconate
- Use of charcoal and gastric lavage in some cases
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in cool, dry place away from light