Dipicard 10 mg (Tablet)
Unit Price: ৳ 7.00 (30's pack: ৳ 210.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- Essential hypertension
- Angina pectoris
- Vasospastic angina
- Monotherapy
- Combination therapy
Pharmacology
- Calcium-channel blocker
- Long duration of action
- Vasodilation
- Reduced peripheral resistance
- Increased coronary blood flow
- Myocardial oxygen supply
Dosage & Administration
- Usual dose 5 mg once daily
- Maximum dose 10 mg once daily
- Lower dose for elderly
- Administration without regard to meals
Interaction
- Potentially hazardous interactions with p-blockers
- No interaction with Digoxin
- No interaction with Cimetidine
- No significant alteration of Warfarin effect
- No alteration by food
Contraindications
- Hypersensitivity to dihydropyridine derivatives
- Pregnancy
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Gastrointestinal disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Mental depression
- Ischaemic chest pain
- Excessive fall in blood pressure
- Rashes
- Fever
- Abnormalities in liver function
Pregnancy & Lactation
- Pregnancy Category C
- Use if benefit justifies risk
- Discontinue nursing while administered
Precautions & Warnings
- Hepatic impairment precaution
- Pregnancy precaution
- Breastfeeding precaution
Use in Special Populations
- Children (6-17 years) starting dose 2.5 mg
- Elderly well-tolerated
- Renal impairment dose not correlated
- Hepatic impairment dose selection caution
- Severe hepatic impairment initiation at lowest dose
Overdose Effects
- Excessive peripheral vasodilatation
- Reflex tachycardia
- Systemic hypotension
- Shock
- Fatal outcome potential
- Active cardiovascular support required
- Monitoring of cardiac and respiratory function
- Elevation of extremities
- Attention to circulating fluid volume and urine output
- Vasoconstrictor may be helpful
- Intravenous calcium gluconate may be beneficial
- Gastric lavage may be worthwhile
- Activated charcoal may reduce absorption rate
- Dialysis not likely to be beneficial
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protected from light