Rantop 150 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Novus pharmaceuticals ltd |
Title and Categories
- Rantop Tablet
- Gastric Medication
Dimensions
Varies based on packaging
Color Options
N/A
Functions
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
- Post operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastro-intestinal haemorrhage from stress ulcer in seriously ill patient
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patient considered to be at risk of acid aspiration particularly obstetric patients
- Block histamine at H2-receptors of the gastric parietal cells
- Inhibit gastric acid secretion
- Does not affect pepsin secretion
- Competitively blocks histamine at H2-receptors of the gastric parietal cells
- Inhibits gastric acid secretion
- Slow intravenous injection
- Intermittent intravenous infusion at a rate of 25 mg per hour for two hours
Materials
- Ranitidine
Technical Specifications
- 150 mg tablet
- 300 mg tablet
- Duodenal and gastric ulcer dosage: 150 mg twice daily taken in the morning and evening or 300 mg as a single daily dose at night for 4 to 8 weeks
- Reflux oesophagitis dosage: 150 mg twice daily or 300 mg at bedtime for up to 8 weeks
- Zollinger Ellison syndrome dosage: 150 mg 3 times daily and increased if necessary up to 6 g daily in divided doses
- Episodic dyspepsia dosage: 150 mg twice daily or 300 mg at bedtime for up to 6 weeks
- Maintenance dosage: 150 mg at night for preventing recurrences
- 2-4 mg/kg children's dosage twice daily, maximum 300 mg daily
- Prophylaxis of haemorrhage from stress ulceration in seriously ill patients
- Prophylaxis of recurrent haemorrhage in patients bleeding from peptic ulceration
- Pregnancy usage essential
- Lactation usage with caution
- Reduced dosage for patients with impaired renal and hepatic function
- Storage: cool and dry place, protect from light
Design Elements
- Tablet
- Syrup
- IV injection
- IV Infusion
Usability Features
- Well-tolerated
- Rare side effects
- Specific action
Interactions
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of coumarin anticoagulants, theophylline, diazepam and propanolol
- May alter absorption of pH-dependent drugs (e.g. ketoconazole, midazolam, glipizide)
- May reduce bioavailability with antacids
Pregnancy & Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the foetus
- Caution during lactation
Contraindications
- Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Precautions & Warnings
- Use reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No significant difference in adverse effects in elderly patients
Overdose Effects
- Specific action minimizes problems
- Symptomatic and supportive therapy if needed
- Hemodialysis if required
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Slow IV injection method
- Intermittent slow IV infusion method
- Continuous IV infusion method
Storage Conditions
- Cool and dry place
- Protect from light