Recodin 150 mg (Tablet)
Unit Price: ৳ 2.50 (15 x 10: ৳ 375.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Concord pharmaceuticals ltd |
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Post-operative stress ulcer
- Zollinger-Ellison Syndrome
- Gastroesophageal reflux disease (GERD)
- Gastrointestinal haemorrhage in seriously ill patients
- Recurrent haemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patients at risk of acid aspiration
Pharmacology
- Competitive blockade of histamine at H2-receptors
- Inhibition of gastric acid secretion
- No effect on pepsin secretion
- No effect on pentagastrin-stimulated intrinsic factor secretion
- No effect on serum gastrin
Dosage & Administration
- Usual dosage of 150 mg twice daily for duodenal and gastric ulcer
- Usual dosage of 150 mg twice daily for reflux oesophagitis
- Usual dosage of 150 mg 3 times daily for Zollinger-Ellison syndrome
- Usual dosage of 150 mg twice daily for episodic dyspepsia
- Maintenance dosage of 150 mg at night for preventing recurrences
- Dosage of 2-4 mg/kg twice daily for peptic ulcer in children
- IV injection may be given as a slow intravenous injection
- IV infusion at a rate of 25 mg per hour for two hours
- Intramuscular injection every six to eight hours
- Recommended oral dose for children is 2 mg/kg to 4 mg/kg twice daily
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimal inhibition of hepatic metabolism of certain drugs
- Alteration of absorption of pH-dependent drugs
- Reduced bioavailability with antacids
Contraindications
- Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy & Lactation
- Crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Use only if considered essential during pregnancy
- Excreted in human breast milk
- Caution should be exercised when administered to a nursing mother
Precautions & Warnings
- Given in reduced dosage to patients with impaired renal and hepatic function
Use in Special Populations
- Similar ulcer healing rates in elderly patients
- No difference in the incidence of adverse effects in elderly patients
Overdose Effects
- Specific action with no particular problems expected following overdosage
- Symptomatic and supportive therapy should be given as appropriate
- May be removed from the plasma by haemodialysis if required
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Specific reconstitution instructions for slow IV inj, intermittent slow IV infusion, continuous IV infusion
- Special dilution for patients with hypersecretory conditions
Storage Conditions
- Store in a cool and dry place
- Protect from light