SB-Amloator 5 mg+10 mg (Tablet)
Unit Price: ৳ 11.00 (30's pack: ৳ 330.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atorvastatin |
| Company | Sunman birdem pharma ltd |
Title
- Amlodipine and Atorvastatin Combination Tablet
Categories
- Cardiovascular Medication
- Cholesterol Management
- Hypertension Treatment
Description
- A combination product containing Amlodipine Besilate and Atorvastatin calcium
- Indicated for hypertension, chronic stable angina, hypercholesterolemia, and reducing the risk of nonfatal MI and stroke
Dimensions
- 6mm x 3mm x 1mm
Color Options
- White
Functions
- Lowers blood pressure
- Reduces cholesterol levels
- Prevents angina attacks
Materials
- Amlodipine Besilate
- Atorvastatin calcium
Dosage
- Amlodipine: 5mg once daily, maximum 10mg once daily
- Atorvastatin: 10mg to 80mg once daily
Pharmacology
- Amlodipine: Peripheral arterial vasodilator
- Atorvastatin: HMG-CoA reductase inhibitor
Interaction
- Can interact with cyclosporine, fibric acid derivatives, erythromycin, and antacid suspension
Contraindications
- Amlodipine: Known hypersensitivity
- Atorvastatin: Contraindicated in active liver disease
Side Effects
- Amlodipine: Hypotension, caution in heart failure patients
- Atorvastatin: Elevation in serum creatine phosphokinase levels, myalgia
Pregnancy & Lactation
- Safety not established during pregnancy, not recommended during breastfeeding
Precautions & Warnings
- Increased angina and/or myocardial infarction in some patients
- HMG-CoA reductase inhibitors associated with liver function abnormalities
Use in Special Populations
- Pediatrics: Safety and efficacy not established in children
Therapeutic Class
- Anti-anginal & lipid lowering drugs
Storage Conditions
- Store in a cool, dry place
- Protect from light and moisture
- Keep out of reach of children
Usability Features
- Suitable for hypertension and hypercholesterolemia management
Packaging
- Blister pack
- Bottle
Age Range
- Adults
Prescription Type
- Prescription required
Administration
- Oral administration
Adverse Effects
- Constipation
- Flatulence
- Dyspepsia
- Nausea
- Insomnia
- Abdominal pain
- Headache
Symptoms Relief
- Reduces angina frequency and severity
Patient Monitoring
- Monitor serum transaminase levels
Heart Health Benefits
- Reduces the risk of nonfatal MI and stroke
Delivery Form
- Tablet
Special Instructions
- Caution in patients with aortic stenosis
- Monitor for myopathy and chest pain
Compatibility
- Compatible with most antihypertensive drugs
Blood Pressure Regulation
- Lowers blood pressure
Cholesterol Management
- Lowers LDL, total cholesterol, and triglyceride levels
Elderly Dosage
- 2.5mg once daily for Amlodipine
Renal Insufficiency
- No dose adjustment required for Atorvastatin
Gastrointestinal Tolerance
- May cause constipation, flatulence, dyspepsia
Liver Function Monitoring
- Monitor for biochemical abnormalities of liver function
Skeletal Muscle Health
- Monitor for myopathy and elevated CPK levels
Clinical Studies
- Shown to not lead to clinical deterioration in heart failure patients
Drug Effectiveness
- Proven to reduce frequency and severity of angina
Lipid Profile Management
- Reduces LDL-C, HDL-C, and TG levels
Calcium Channel Blocker
- Amlodipine acts directly on vascular smooth muscle to reduce blood pressure
Synthetic Lipid-lowering Agent
- Atorvastatin inhibits HMG-CoA reductase to reduce cholesterol synthesis
Adherence Reminder
- Take the medication at the same time daily
Food Interaction
- Atorvastatin can be taken with or without food
Storage Duration
- 36 months
Dose Adjustment
- According to individual patient's need
Special Population Safety
- Efficacy and safety similar in older patients
Hypotension Caution
- Exercised when administering Amlodipine
Heart Failure Patients
- Use calcium channel blockers with caution
Disease-specific Dosage
- Lower dosage suggested for the elderly and patients with hepatic insufficiency