AV 5 mg+80 mg (Tablet)
Unit Price: ৳ 7.00 (3 x 14: ৳ 294.00)
Strip Price: ৳ 98.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate valsartan |
| Company | Drug international ltd |
| Also available as |
Indications
- Treatment of hypertension
Pharmacology
- Amlodipine is a dihydropyridine calcium channel blocker
- Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II
Dosage & Administration
- Once daily doses of 2.5 mg - 10 mg for Amlodipine
- Doses of 80 mg-320 mg for Valsartan
- Antihypertensive effects increase with increasing doses
- Majority of the antihypertensive effect is attained within 2 weeks
- Dosage can be increased to a maximum of 10/320 mg once daily
- May be administered with or without food
- May be administered with other antihypertensive agents
- Initiation at 2.5 mg for elderly patients
- No initial dosage adjustment for patients with mild or moderate renal impairment
- Titrate slowly in patients with severe renal or hepatic impairment
Interaction
- No drug interaction studies conducted with Amlodipine and Valsartan combination
Contraindications
- Hypersensitivity to any components
Side Effects
- Mild and transient in nature
- Common side effects include peripheral edema, nasal congestion, sore throat, discomfort when swallowing, upper respiratory tract infection, dizziness
Pregnancy & Lactation
- Pregnancy Category D
- It is not known whether Amlodipine or Valsartan is excreted in human milk
- Risk assessment for nursing mothers
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Assess for hypotension
- Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction
- Titrate slowly in patients with impaired hepatic or severely impaired renal function
Use in Special Populations
- Safety and effectiveness in paediatric patients not established
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children