AV 5 mg+80 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 14: ৳ 294.00)
Strip Price: ৳ 98.00

Medicine Details

Category Details
Generic Amlodipine besilate valsartan
Company Drug international ltd
Also available as
Av 5 mg tablet Av 10 mg tablet

Indications

  • Treatment of hypertension

Pharmacology

  • Amlodipine is a dihydropyridine calcium channel blocker
  • Valsartan blocks the vasoconstrictor and aldosterone-secreting effects of Angiotensin II

Dosage & Administration

  • Once daily doses of 2.5 mg - 10 mg for Amlodipine
  • Doses of 80 mg-320 mg for Valsartan
  • Antihypertensive effects increase with increasing doses
  • Majority of the antihypertensive effect is attained within 2 weeks
  • Dosage can be increased to a maximum of 10/320 mg once daily
  • May be administered with or without food
  • May be administered with other antihypertensive agents
  • Initiation at 2.5 mg for elderly patients
  • No initial dosage adjustment for patients with mild or moderate renal impairment
  • Titrate slowly in patients with severe renal or hepatic impairment

Interaction

  • No drug interaction studies conducted with Amlodipine and Valsartan combination

Contraindications

  • Hypersensitivity to any components

Side Effects

  • Mild and transient in nature
  • Common side effects include peripheral edema, nasal congestion, sore throat, discomfort when swallowing, upper respiratory tract infection, dizziness

Pregnancy & Lactation

  • Pregnancy Category D
  • It is not known whether Amlodipine or Valsartan is excreted in human milk
  • Risk assessment for nursing mothers

Precautions & Warnings

  • Avoid fetal or neonatal exposure
  • Assess for hypotension
  • Warn patients with severe obstructive coronary artery disease about the risk of myocardial infarction
  • Titrate slowly in patients with impaired hepatic or severely impaired renal function

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture
  • Keep out of the reach of children

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