Cardotel 5 mg+80 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 14: ৳ 560.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate telmisartan |
| Company | Pharmasia limited |
| Also available as |
Indications
- Treatment of hypertension
- Used as initial therapy in patients needing multiple drugs for blood pressure goals
Pharmacology
- Combination of Telmisartan and Amiodipine
- Telmisartan is an angiotensin receptor blocker
- Amiodipine is a calcium-channel blocker
- Telmisartan blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
- Amiodipine inhibits calcium ion influx into vascular and cardiac muscle
Dosage & Administration
- 40/5 mg or 80/5 mg once daily for initial therapy
- Add-on therapy for patients not adequately controlled with single agents
- Replacement therapy for patients receiving separate tablets of amiodipine and telmisartan
- Maximum recommended dose of 80/10 mg once daily
Interaction
- No clinically significant interaction with acetaminophen, glyburide, simvastatin, hydrochlorothiazide, warfarin, or ibuprofen
- Possible inhibition of CYP2C19 metabolism
- Amiodipine safely administered with various drugs
Contraindications
- Hypersensitivity to the product or its components
- Pregnancy & lactation
- Biliary obstructive disorders, severe hepatic impairment, hypotension, cardiogenic shock
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Hypotension
- Cough
- Abdominal pain
- Erectile dysfunction
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Not known whether excreted in human milk
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct any volume or salt depletion before therapy
- Monitor for worsening heart failure
- Avoid concomitant use of an ACE inhibitor and angiotensin receptor blocker
Use in Special Populations
- Not established for pediatric use
- Not recommended for patients ≥75 years old
- Not recommended for hepatically impaired patients
Overdose Effects
- Telmisartan overdosage manifestations: hypotension, dizziness, tachycardia
- Amiodipine overdosage manifestations: excessive peripheral vasodilation, marked hypotension, reflex tachycardia
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children