Orbapin 5 mg+20 mg (Tablet)

Unit Price: ৳ 12.00 (5 x 10: ৳ 600.00)
Strip Price: ৳ 120.00

Medicine Details

Title

Orbapin

Categories

  • Medicine
  • Antihypertensive

Description

Orbapin is indicated for the treatment of hypertension alone or with other antihypertensive agents, to lower blood pressure. It can be used as initial therapy in patients likely to need multiple antihypertensive agents to achieve their blood pressure goals. Orbapin is a combination of Amlodipine and Olmesartan Medoxomil that acts as a dihydropyridine calcium channel blocker and an angiotensin II receptor antagonist, respectively.

Indications

  • Treatment of hypertension
  • Initial therapy
  • Blood pressure goals

Pharmacology

  • Dihydropyridine calcium channel blocker
  • Vasodilator
  • ACE inhibitor
  • Vasoconstrictor blocking effects

Dosage & Administration

  • Initial therapy with 5/20 mg
  • Titration
  • Maximum dose of 10/40 mg
  • Special dosing for elderly patients

Interaction

  • Attenuation by NSAIDs
  • Monitoring of blood pressure and renal function

Contraindications

  • Co-administration with Aliskiren in diabetes patients

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy & Lactation

  • Pregnancy Category D
  • Fetal death risk
  • Discontinuation during pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Risk of hypotension
  • Vasodilation risk
  • Increased angina or acute MI risk
  • Use caution in special populations

Use in Special Populations

  • Pediatric use not established
  • No age-related differences
  • No studies in renal impairment
  • Initial therapy not recommended in hepatic impairment

Overdose Effects

  • No human overdose information available

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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