Duoblock 5 mg+20 mg (Tablet)

Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00

Medicine Details

Indications

  • Treatment of hypertension
  • Lowering blood pressure

Pharmacology

  • Amlodipine - calcium channel blocker
  • Olmesartan Medoxomil - angiotensin II receptor blocker
  • Vascular smooth muscle vasodilation
  • Reduction in peripheral vascular resistance

Dosage & Administration

  • Initial therapy with 5/20 mg once daily
  • Titration up to a maximum of 10/40 mg once daily
  • Different dosing for elderly patients

Interaction

  • Possible attenuation by NSAIDs including selective COX-2 inhibitors

Contraindications

  • Co-administration with Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy & Lactation

  • Pregnancy Category D
  • Avoid use in 2nd and 3rd trimester
  • Discontinue when pregnancy is detected
  • Uncertainty about excretion in human milk

Precautions & Warnings

  • Risk of hypotension in volume- or salt-depleted patients
  • Risk of vasodilation in patients with severe aortic stenosis
  • Risk of increased angina or acute MI in patients with severe obstructive coronary artery disease

Use in Special Populations

  • Pediatric use not established
  • No overall differences in safety or effectiveness in elderly patients
  • No studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No information available on overdose in humans

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Do not store above 30°C
  • Keep away from light
  • Keep out of the reach of children

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