Duoblock 5 mg+20 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Aristopharma ltd |
| Also available as |
Indications
- Treatment of hypertension
- Lowering blood pressure
Pharmacology
- Amlodipine - calcium channel blocker
- Olmesartan Medoxomil - angiotensin II receptor blocker
- Vascular smooth muscle vasodilation
- Reduction in peripheral vascular resistance
Dosage & Administration
- Initial therapy with 5/20 mg once daily
- Titration up to a maximum of 10/40 mg once daily
- Different dosing for elderly patients
Interaction
- Possible attenuation by NSAIDs including selective COX-2 inhibitors
Contraindications
- Co-administration with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoid use in 2nd and 3rd trimester
- Discontinue when pregnancy is detected
- Uncertainty about excretion in human milk
Precautions & Warnings
- Risk of hypotension in volume- or salt-depleted patients
- Risk of vasodilation in patients with severe aortic stenosis
- Risk of increased angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Pediatric use not established
- No overall differences in safety or effectiveness in elderly patients
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information available on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children