Sutac 150 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Ranitidine hydrochloride |
| Company | Supreme pharmaceutical ltd |
Title
- Sutac
- Ranitidine Tablet
- Ranitidine Syrup
- Ranitidine IV Injection
- Ranitidine IV Infusion
Categories
- Gastric Ulcer Treatment
- Dyspepsia Treatment
- Gastroesophageal Reflux Disease (GERD) Treatment
- Peptic Ulcer Treatment
- Stress Ulcer Prophylaxis
Dosage Forms
- Tablet
- Syrup
- IV Injection
- IV Infusion
Dosage and Administration
- 150 mg twice daily for duodenal and gastric ulcers
- 300 mg once daily at night for 4 to 8 weeks for duodenal and gastric ulcers
- 150 mg twice daily for reflux oesophagitis
- 300 mg at bedtime for up to 8 weeks for reflux oesophagitis
- 150 mg 3 times daily, increased if necessary for Zollinger-Ellison syndrome
- Episodic dyspepsia - 150 mg twice daily or 300 mg at bedtime for up to 6 weeks
- 150 mg at night for maintenance to prevent recurrences
- IV injection may be given as a slow intravenous injection of 50 mg over a period of at least two minutes
- IV infusion at a rate of 25 mg per hour for two hours
- 50 mg intramuscular injection every six to eight hours
- 2-4 mg/kg orally twice daily for children with peptic ulcer
- 50 mg as intravenous injection followed by a continuous intravenous infusion for upper gastrointestinal haemorrhage prophylaxis
- 50 mg intramuscularly or by slow intravenous injection 45 to 60 minutes before induction of general anesthesia in patients at risk of developing aspiration syndrome
Pharmacology
- Competitively blocks histamine at H2-receptors of gastric parietal cells
Indications
- Treatment of active duodenal ulcer
- Benign gastric ulcer
- Ulcer associated with non-steroidal anti-inflammatory agent
- Postoperative stress ulcer
- Zollinger-Ellison Syndrome
- GERD
- Gastrointestinal hemorrhage from stress ulcer
- Recurrent hemorrhage in patients with bleeding peptic ulcer
- Before general anesthesia in patients considered to be at risk of acid aspiration
- Reflux oesophagitis
- Episodic dyspepsia
Interaction
- Delayed absorption and increased peak serum concentration with propantheline bromide
- Minimally inhibits hepatic metabolism of certain drugs
- May alter absorption of pH-dependent drugs
- May reduce bioavailability with antacids
Contraindications
- Hypersensitivity to Ranitidine
Side Effects
- Altered bowel habit
- Dizziness
- Rash
- Tiredness
- Reversible confusional states
- Headache
- Decreased blood counts
- Muscle or joint pain
Pregnancy and Lactation
- Ranitidine crosses the placenta
- No evidence of impaired fertility or harm to the fetus
- Use during pregnancy only if considered essential
- Excreted in human breast milk
- Caution should be exercised when administered to a nursing mother
Precautions and Warnings
- Reduced dosage for patients with impaired renal and hepatic function
Use in Special Populations
- Use in elderly patients - ulcer healing rates similar to younger patients
- No difference in the incidence of adverse effects in elderly patients
Overdose Effects
- No particular problems expected following overdosage
- Symptomatic and supportive therapy may be given
- Haemodialysis may be used if required
Therapeutic Class
- H2 receptor antagonist
Reconstitution
- Different dilution methods for IV administration
Storage Conditions
- Cool and dry place
- Protect from light