Olmesta M 5 mg+20 mg (Tablet)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Amlodipine besilate olmesartan medoxomil
Company Eskayef pharmaceuticals ltd
Also available as
Olmesta m 5 mg tablet

Title

  • Olmesta M-Amlodipine and Olmesartan Medoxomil Combination

Categories

  • Medicine
  • Antihypertensive
  • Pharmacology

Description

  • Olmesta M is indicated for the treatment of hypertension alone or with other antihypertensive agents to lower blood pressure.

Indications

  • Treatment of hypertension alone or with other antihypertensive agents
  • Lowering blood pressure
  • Initial therapy for patients likely to need multiple antihypertensive agents

Mode of Action

  • Dihydropyridine calcium channel blocker
  • Inhibition of transmembrane influx of calcium ions
  • Peripheral arterial vasodilator
  • Blockage of vasoconstrictor and aldosterone-secreting effects of angiotensin II

Dosage and Administration

  • Initial therapy with 5/20 mg once daily
  • Maximum dosage of 10/40 mg once daily
  • Individual titration of components
  • Increased amount of Amlodipine or Olmesartan Medoxomil as needed

Interaction

  • Attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors

Contraindications

  • Co-administration with Aliskiren in patients with diabetes

Side Effects

  • Peripheral edema
  • Headache
  • Flushing
  • Dizziness
  • Sprue-like enteropathy

Pregnancy and Lactation

  • Pregnancy Category D
  • Avoid use in 2nd and 3rd trimester
  • Potential excretion in human milk

Precautions and Warnings

  • Risk of hypotension in volume- or salt-depleted patients
  • Vasodilation in patients with severe aortic stenosis
  • Increased frequency, duration, or severity of angina or acute MI in patients with severe obstructive coronary artery disease

Use in Special Populations

  • No established safety and effectiveness in pediatric patients
  • No overall differences in safety or effectiveness in subjects 65 years of age or older
  • No studies in patients with renal impairment
  • Initial therapy not recommended in hepatically impaired patients

Overdose Effects

  • No information available on overdose in humans

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Store below 30°C
  • Keep away from light
  • Keep out of the reach of children

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