Calsart 5 mg+20 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Globe pharmaceuticals ltd |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized decision for combination therapy based on patient's risk
Pharmacology
- Amlodipine as dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Substitute individually titrated components
- Initiate with 5/20 mg once daily and titrate as needed
- Recommended starting dose of Amlodipine is 2.5 mg for patients 75 years or older
Interaction
- Attenuation of antihypertensive effect by NSAIDs including selective COX-2 inhibitors
- Monitoring of blood pressure, renal function, and electrolytes for combination therapy
Contraindications
- Cannot be co-administered with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoid use in 2nd and 3rd trimester
- Discontinue when pregnancy is detected
- Unknown excretion of Olmesartan and Amlodipine in human milk
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Risk of vasodilation in patients with severe aortic stenosis
- Increased risk of angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
- No overall differences in safety or effectiveness in geriatric use
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children