Duopres 5 mg+40 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension
- Lowering of blood pressure
- Initial therapy
- Individualized blood pressure goals
Pharmacology
- Dihydropyridine calcium channel blocker
- Vascular smooth muscle effect
- Peripheral arterial vasodilator
- Blocker of angiotensin II effects
- Aldosterone secretion inhibitor
- Competitive inhibitor of AT1 receptor
Dosage & Administration
- Substitute individually titrated components
- Initial therapy with 5/20 mg once daily
- Titration as needed
- Maximum dosage of 10/40 mg once daily
- Lower starting dose for elderly patients
Interaction
- Attenuation by NSAIDs
- Monitoring of blood pressure, renal function, and electrolytes
Contraindications
- Co-administration with Aliskiren in diabetes patients
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Fetal death risk
- Excretion in human milk
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Vasodilation risk in severe aortic stenosis
- Angina and acute MI risk in severe obstructive coronary artery disease
Use in Special Populations
- Pediatric use not established
- No overall differences in geriatric use
- No studies in patients with renal impairment
- Not recommended in hepatically impaired patients
Overdose Effects
- No information on human overdose
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children