Ariprex 2 mg (Tablet)
Unit Price: ৳ 2.00 (6 x 5: ৳ 60.00)
Strip Price: ৳ 10.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Aripiprazole |
| Company | Square pharmaceuticals plc |
| Also available as |
Title
- Ariprex
Categories
- Medicine
- Antipsychotic
- Pharmacotherapy
Description
- Aripiprazole medication indicated for schizophrenia, bipolar disorder, major depressive disorder, irritability associated with autistic disorder, and agitation associated with schizophrenia or bipolar mania
Indications
- Schizophrenia
- Bipolar disorder
- Major depressive disorder
- Autistic disorder irritability
- Schizophrenia or bipolar mania agitation
Mode of Action
- Partial agonist activity at Dopamine D2 receptors
- Partial agonist activity at Serotonin 5-HT 1A receptors
- Antagonist activity at Serotonin 5-HT 2A receptors
Dosage
- Initial dose range for schizophrenia in adults: 10-15 mg/day
- Recommended dose for bipolar mania in adults: 15 mg/day
- Maximum dose for all indications: 30 mg/day
Administration
- Oral formulations administered once daily without regard to meals
- IM injection with a minimum 2-hour interval between doses, maximum daily dose 30 mg
Interactions
- Caution with other centrally acting drugs and alcohol
- Carbamazepine may increase Aripiprazole clearance
- Ketoconazole, quinidine, fluoxetine or paroxetine may inhibit Aripiprazole elimination
Contraindications
- Known hypersensitivity to Aripiprazole
Side Effects
- Vomiting
- Nausea
- Akathisia
- Extrapyramidal disorder
- Somnolence
- Sedation
- Dizziness
- Insomnia
- Tremor
- Restlessness
- Fatigue
- Blurred vision
- Salivary hypersecretion
- Constipation
- Pyrexia
- Drooling
- Decreased appetite
Pregnancy & Lactation
- Pregnancy category C
- Avoid during pregnancy
- Not recommended for breastfeeding women
Precautions & Warnings
- Increased incidence of cerebrovascular adverse events in elderly patients with dementia-related psychosis
- Increased risk of suicidality with antidepressants in children, adolescents, and adults with major depressive disorder
- Discontinue if clinically appropriate for tardive dyskinesia
- Atypical antipsychotic drugs associated with metabolic changes
- Use with caution in patients with known cardiovascular or cerebrovascular disease
- Use cautiously in patients with a history of seizures
- Caution when operating machinery
Overdose Effects
- No fatalities observed with doses up to 1080 mg
- Signs and symptoms include nausea, vomiting, asthenia, diarrhea, and somnolence
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep below 30°C temperature
- Keep away from light & moisture
- Keep out of the reach of children