Zorep 150 mg (Tablet)

Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)

Medicine Details

Indications

  • Treatment of active duodenal ulcer
  • Benign gastric ulcer
  • Treatment & prevention of ulcer associated with non-steroidal anti-inflammatory agent
  • Postoperative stress ulcer
  • Zollinger-Ellison Syndrome
  • Gastroesophageal reflux disease (GERD)
  • Gastrointestinal hemorrhage from stress ulcer in seriously ill patients
  • Recurrent hemorrhage in patients with bleeding peptic ulcer

Pharmacology

  • Competitively blocks histamine at H2-receptors of the gastric parietal cells
  • Inhibits gastric acid secretion
  • Does not affect pepsin secretion or serum gastrin

Dosage & Administration

  • Dosage for duodenal and gastric ulcer
  • Dosage for reflux esophagitis
  • Dosage for Zollinger-Ellison syndrome
  • Dosage for episodic dyspepsia
  • Maintenance dosage
  • Children's dosage
  • IV injection dosage
  • IV infusion dosage

Interaction

  • Delayed absorption
  • Increased peak serum concentration with propantheline bromide
  • Minimally inhibits hepatic metabolism of certain drugs
  • May alter absorption of pH-dependent drugs
  • May reduce bioavailability with antacids

Contraindications

  • Patients hypersensitive to Ranitidine

Side Effects

  • Altered bowel habit
  • Dizziness
  • Rash
  • Tiredness
  • Reversible confusional states
  • Headache
  • Decreased blood counts
  • Muscle or joint pain

Pregnancy & Lactation

  • Crosses the placenta
  • No evidence of impaired fertility or harm to the fetus
  • Excreted in human breast milk
  • Caution required during nursing

Precautions & Warnings

  • Reduced dosage for patients with impaired renal and hepatic function

Use in Special Populations

  • Use in elderly patients

Overdose Effects

  • Specific in action
  • Symptomatic and supportive therapy may be necessary
  • Potential for removal via hemodialysis

Therapeutic Class

  • H2 receptor antagonist

Reconstitution

  • Instructions for reconstituting for slow IV injection
  • Instructions for reconstituting for intermittent slow IV infusion
  • Instructions for reconstituting for continuous IV infusion

Storage Conditions

  • Store in cool and dry place
  • Protect from light

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