Anol 50 mg (Tablet)
Unit Price: ৳ 0.77 (100's pack: ৳ 77.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atenolol |
| Company | Modern pharmaceuticals ltd |
Title
- Anol Tablets
Categories
- Hypertension Medication
- Angina Pectoris Medication
- Myocardial Infarction Medication
- Beta-blocker
Indications
- Management of hypertension
- Long-term management of patients with angina pectoris
- Management of hemodynamically stable patients with acute myocardial infarction
Mode of Action
- Competitively blocks beta1 (cardiac) receptors
- Beta1 selective (cardioselective) beta-adrenergic receptor antagonist
- Markedly hydrophilic
- Poorly penetrates lipid cell membranes
Dosage and Administration
- Initial dose of 50mg for hypertension
- Initial dose of 50mg for angina pectoris
- Initial intravenous dose for acute myocardial infarction followed by oral doses
Interaction
- Additive effect with catecholamine-depleting drugs
- Additive effect with calcium channel blockers
- Potential negative effects with disopyramide and amiodarone
- Exacerbates rebound hypertension when coadministered with clonidine
- Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
- Risk of severe allergic reaction in patients with a history of anaphylaxis
- Increased risk of bradycardia when used with digitalis glycosides
Contraindications
- Sinus bradycardia
- Greater than first degree heart block
- Cardiogenic shock
- Overt cardiac failure
- Hypersensitivity to atenolol or any of the drug's components
Side Effects
- Agranulocytosis
- Allergic reactions
- Reversible mental depression
- Ischemic colitis
- Skin rashes and dry eyes
- Erythematous rash
Pregnancy and Lactation
- Pregnancy Category D
- Clinically significant bradycardia reported in breast-fed infants
Precautions and Warnings
- Evaluation required for patients already on beta blocker therapy
- Aggravates peripheral arterial circulatory disorders
- Caution needed in patients with impaired renal function
- Dose adjustment for elderly patients and patients with renal impairment
Use in Special Populations
- Dosage adjustment for elderly and renal impaired patients
- Maximum oral dosages recommended for different levels of renal impairment
- Lower starting dose for some renal impaired or elderly patients
Overdose Effects
- Reported overdoses surviving acute doses as high as 5g
- Symptoms include lethargy, respiratory disorder, wheezing, sinus pause, and bradycardia
- Treatment includes removal of unabsorbed drug and supportive care
Therapeutic Class
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Do not use after expiry date
- Keep out of reach of children
- Dispensed only on prescription of a registered physician