Misotol 200 mcg (Tablet)
Unit Price: ৳ 15.00 (2 x 10: ৳ 300.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Misoprostol |
| Company | Ziska pharmaceuticals ltd |
Indications
- Prophylaxis of gastric and duodenal ulceration in NSAID users at high risk of complications
- Healing of established NSAID-induced gastric and duodenal damage
- Induction of labor
- Prevention and treatment of postpartum hemorrhage
Pharmacology
- Rapid de-esterification to its free acid
- Maximized plasma concentrations with food intake
- Antisecretory properties
- Mucosal protective properties
- Increase in bicarbonate and mucus production
Dosage & Administration
- Dosage for benign gastric and duodenal ulceration and NSAID associated ulceration
- Dosage for prophylaxis of NSAID-induced gastric and duodenal ulcer
- Dosage for induction of labor
- Dosage for prevention of postpartum hemorrhage
- Dosage for treatment of postpartum hemorrhage
Interaction
- No clinically significant interaction with cardiac, pulmonary, CNS drugs and NSAIDs
- Decreased bioavailability with high doses of antacid
Contraindications
- History of allergy to prostaglandins
- Pregnancy
Side Effects
- Adverse effects associated with the GI tract
- Diarrhea
- Abdominal pain
- Dyspepsia
- Flatulence
- Nausea
- Vomiting
- Rashes
- Dizziness
Pregnancy & Lactation
- Abortifacient property
- Contraindicated in pregnant women
- Prescribed with negative serum pregnancy test
- Effective contraceptive measures required
- Oral and written warnings of hazards
- Excretion of active metabolite into milk
Precautions & Warnings
- Contraindicated in pregnant women for NSAID induced gastric and duodenal ulcer
- Contraindicated in women of childbearing potential
- Effective contraception method required during therapy
- Requirements for induction of labor
- Contraindications for induction of labor
Use in Special Populations
- Safety and effectiveness in children below 18 years not established
Overdose Effects
- Toxic dose not determined
- Clinical signs of overdose
- Symptom treatment with supportive therapy
Therapeutic Class
- Drugs acting on the Uterus
- Prostaglandin analogues
Storage Conditions
- Cool and dry place
- Protected from light and moisture
- Keep out of reach of children