Tanzil 40 mg (Tablet)
Unit Price: ৳ 12.00 (1 x 14: ৳ 168.00)
Strip Price: ৳ 168.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azilsartan medoxomil |
| Company | Drug international ltd |
Indications
- treatment of hypertension
- lowering blood pressure
- reduce risk of cardiovascular events
- can be used alone or in combination with other antihypertensive agents
Pharmacology
- formation and effects of angiotensin II
- blockade of vasoconstrictor and aldosterone-secreting effects
- inhibition of renin-angiotensin system
- absorption, distribution, metabolism, and elimination
- plasma concentrations and protein binding
Dosage & Administration
- recommended dose for adults
- consider starting dose for patients treated with high doses of diuretics
- additional blood pressure reduction with other antihypertensive agents
Interaction
- no observed drug interactions with specific drugs
- potential attenuation of antihypertensive effect by non-steroidal anti-inflammatory drugs
- risk of hypotension, hyperkalemia, and changes in renal function with dual blockade of the RAS
Contraindications
- contraindicated co-administration with Aliskiren in patients with diabetes
Side Effects
- common adverse reaction of diarrhea
- other side effects including nausea, asthenia, fatigue, muscle spasm, dizziness, and cough
Pregnancy & Lactation
- Pregnancy Category D
- risk to fetus in second or third trimester
- potential excretion of Azilsartan Medoxomil in human milk
Precautions & Warnings
- reduced fetal renal function and increased fetal and neonatal morbidity and death during second and third trimesters of pregnancy
- potential hypotension in intravascularly volume-depleted patients
- changes in renal function including renal failure in renal impaired patient
Use in Special Populations
- neonatal effects with in utero exposure to Azilsartan
- safety and effectiveness not established in pediatric patients under 18 years of age
- no dose adjustment in elderly patients
- no dose adjustment in patients with mild-to-severe renal impairment or end-stage renal disease
- no dose adjustment in subjects with mild or moderate hepatic impairment
Overdose Effects
- limited data on overdose in humans
- supportive therapy in the event of an overdose
- Tanzil is not dialyzable
Therapeutic Class
- Angiotensin-II receptor blocker
Storage Conditions
- keep in a dry place away from light and heat
- keep out of reach of children