AU-20 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.50 (100's pack: ৳ 450.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Omeprazole |
| Company | Decent pharma laboratories ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Inhibitor of gastric acid secretion
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer
- 20 mg once daily for NSAID-associated duodenal or gastric ulcer
- 20 mg once daily for gastro-esophageal reflux disease
- 10-20 mg daily for long-term management of acid reflux disease
- 10-20 mg once daily for acid-related dyspepsia
- 40 mg for prophylaxis of acid aspiration before surgery
- Initial 60 mg once daily for Zollinger-Ellison syndrome
- 20 mg twice daily for Helicobacter pylori eradication regimen
- Pediatric use: 10-40 mg once daily for severe ulcerating reflux esophagitis
- Intravenous: 40 mg for different indications
Administration
- IV injection for prophylaxis of acid aspiration
- IV infusion for different indications
Interaction
- Decreased intragastric acidity affects ketoconazole absorption
- Metabolized in the liver through cytochrome P450, may affect diazepam, phenytoin, and warfarin
- Increased plasma concentrations during concomitant administration with clarithromycin
- No evidence of interaction with phenacetin, theophylline, caffeine, and more
Contraindications
Known hypersensitivity to Omeprazole
Side Effects
- Skin rash, urticaria, pruritus
- Photosensitivity, bullous eruption, erythema multiforme, angioedema, alopecia
- Diarrhea, headache, constipation, nausea/vomiting, flatulence, abdominal pain
- Dry mouth, stomatitis, candidiasis, paraesthesia
- Dizziness, light headedness, feeling faint, somnolence, insomnia, vertigo
- Reversible mental confusion, agitation, depression, hallucinations
- Arthritic and myalgic symptoms, blurred vision, taste disturbance, peripheral oedema
- Increased sweating, gynaecomastia, leucopenia, thrombocytopenia, and more
Pregnancy & Lactation
Can be used during pregnancy, breastfeeding should be discontinued if essential
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- PPI therapy may be associated with an increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in patients treated long-term with AU-20
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat