Besectil 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.00 (100's pack: ৳ 400.00)
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Bengal drugs ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Action on hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
- Return of secretory activity after discontinuation of the drug
Dosage
- Dosage for benign gastric and duodenal ulcer
- Dosage for NSAID-associated duodenal or gastric ulcer
- Dosage for gastro-esophageal reflux disease
- Dosage for long-term management of acid reflux disease
- Dosage for acid-related dyspepsia
- Dosage for prophylaxis of acid aspiration
- Dosage for Zollinger-Ellison syndrome
- Dosage for Helicobacter pylori eradication regimen in peptic ulcer disease
- Pediatric use in severe ulcerating reflux esophagitis
- Dosage for IV injection
Administration
- Direction for use of IV Injection
- Direction for use of IV Infusion
- Instructions for reconstitution and administration
- Use of freshly prepared solution
- Maximum administration rate
- Limited time for use after reconstitution
Interaction
- Impact on absorption of ketoconazole
- Metabolism through cytochrome P450
- Potential delay in elimination of diazepam, phenytoin, and warfarin
- Monitoring of patients receiving warfarin or phenytoin
- Impact on blood concentration of phenytoin and coagulation time with warfarin
- Plasma concentrations during concomitant administration
- No evidence of interaction with certain drugs
- Impact on the bioavailability of digoxin
Contraindications
- Known hypersensitivity
- Possibility of malignancy in gastric ulcer
Side Effects
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhea and headache
- Gastrointestinal reactions
- Dry mouth, stomatitis, and candidiasis
- Paraesthesia
- Dizziness, light headedness, and feeling faint
- Mental confusion, agitation, and depression
- Arthritic and myalgic symptoms
- Reported cases of blurred vision, taste disturbance, and peripheral edema
- Hepatic and hematologic reactions
Pregnancy & Lactation
- No adverse effects on pregnancy or health of the fetus/newborn child
- Usage recommendation during pregnancy
- No information available on passage into breast milk
- Recommendation to discontinue breastfeeding if essential use
Precautions & Warnings
- Avoid concomitant use of clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Occasional observation of atrophic gastritis in long-term use
- Potential for methotrexate toxicities with concomitant use
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Dry place away from light and heat, keep out of reach of children