SMR 10 mg (Tablet)
Unit Price: ৳ 8.03 (30's pack: ৳ 240.90)
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Amulet pharmaceuticals ltd |
Indications
- Spasticity resulting from multiple sclerosis
- Flexor spasms and concomitant pain, clonus and muscular rigidity
- Skeletal muscle spasm resulting from rheumatic disorders
- Spinal cord injuries and other spinal cord diseases
- Cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- Inhibition of monosynaptic and polysynaptic reflexes
- Stimulation of GABA receptors
- Inhibition of glutamate and aspartate release
- CNS depression
- Antinociceptive effect
Dosage & Administration
- Initial dose for adults and children over 10 years: 5 mg 3 times daily
- Maximum daily dosage: 100 mg
- Gradual dose escalation
- Different dosages for children based on age groups
Interaction
- Increased sedation with CNS agents, alcohol, or synthetic opiates
- Risk of respiratory depression
- Impact on blood pressure when combined with antihypertensives
- Potentiation of effects when combined with tricyclic antidepressants
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Drowsiness
- Daytime sedation
- Dizziness
- Weakness
- Fatigue
- Various CNS effects
- Cardiovascular effects
- Gastrointestinal effects
- Genitourinary effects
- Other rare side effects
Pregnancy & Lactation
- Pregnancy category B3
- Crosses placental barrier
- Excreted in breast milk
- Physician's judgement for administration during pregnancy
- No significant effects on infants
Precautions & Warnings
- Lower doses for patients with impaired renal function
- Caution for patients with psychotic or mood disorders
- Seizure risk in patients with epilepsy
- Monitoring in patients with other medical conditions
- Respiratory and cardiovascular monitoring
- Bladder emptying and urine retention caution
- Stroke patients' poor tolerance to the product
Overdose Effects
- Gastric lavage for severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Temperature below 30°C
- Away from light and moisture
- Keep out of reach of children