Spinax 10 mg (Tablet)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Edruc limited |
Indications
- spasticity resulting from multiple sclerosis
- flexor spasms and concomitant pain
- clonus and muscular rigidity
- skeletal muscle spasm resulting from rheumatic disorders
- spinal cord injuries and other spinal cord diseases
- cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- inhibits both monosynaptic and polysynaptic reflexes
- stimulates GABA receptors
- inhibits release of glutamate and aspartate
- antinociceptive effect
Dosage & Administration
- recommended dosage for adults and children over 10 years
- gradual increase in dosage
- maximum daily dosage
- dosage for children under 10 years
- daily maintenance dose for different age groups
Interaction
- possible interactions with agents acting on the central nervous system
- potential effects on blood pressure when combined with antihypertensives
- interaction with tricyclic antidepressants
- reports of mental confusion and hallucinations when combined with levodopa and carbidopa
- caution advised when used with MAO inhibitors
- potential interaction with magnesium sulfate or other neuromuscular blocking agents
Contraindications
- contraindicated in patients with hypersensitivity to any component
Side Effects
- common adverse reactions
- adverse reactions related to the central nervous system
- cardiovascular adverse reactions
- gastrointestinal adverse reactions
- genitourinary adverse reactions
- other possible adverse reactions
Pregnancy & Lactation
- Pregnancy category B3
- use during pregnancy when potential benefits outweigh possible hazards
- excretion in breast milk
- expected minimal effect on the infant
Precautions & Warnings
- lower doses for patients with impaired renal function
- caution for patients with psychotic disorders, schizophrenia, depressive or manic disorders
- use in patients with epilepsy
- caution in patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
- monitoring of respiratory and cardiovascular function
- caution in patients with preexisting sphincter hypertonia
- limited benefit to stroke patients
- appropriate laboratory tests for patients with hepatic diseases or diabetes mellitus
Overdose Effects
- importance of gastric lavage in cases of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- storage temperature
- protection from light and moisture
- keep out of the reach of children