Deu 40 mg/vial (IV Injection)

40 mg vial: ৳ 80.00

Medicine Details

Category Details
Generic Omeprazole
Company Monicopharma ltd
Also available as
Deu 20 mg capsule

Indications

  • Gastric and duodenal ulcer
  • NSAID-associated duodenal and gastric ulcer
  • Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
  • Gastro-esophageal reflux disease
  • Long-term management of acid reflux disease
  • Acid-related dyspepsia
  • Severe ulcerating reflux esophagitis
  • Prophylaxis of acid aspiration during general anesthesia
  • Zollinger-Ellison syndrome
  • Helicobacter pylori-induced peptic ulcer

Pharmacology

Inhibitor of gastric acid secretion

Dosage

  • Oral administration
  • IV injection

Administration

  • Direction for use of IV Injection
  • Direction for use of IV Infusion

Interaction

  • Decreased intragastric acidity affecting absorption of ketoconazole
  • Metabolism through cytochrome P450 affecting elimination of diazepam, phenytoin, and warfarin
  • Increased plasma concentrations during concomitant administration with clarithromycin
  • No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, or antacids

Contraindications

  • Known hypersensitivity to omeprazole
  • Suspicion of gastric ulcer with possibility of malignancy

Side Effects

  • Skin rash
  • Urticaria
  • Pruritus
  • Photosensitivity
  • Bullous eruption
  • Erythema multiforme
  • Angioedema
  • Alopecia
  • Diarrhea
  • Headache
  • Constipation
  • Nausea
  • Vomiting
  • Flatulence
  • Abdominal pain
  • Dry mouth
  • Stomatitis
  • Candidiasis
  • Paraesthesia
  • Dizziness
  • Lightheadedness
  • Fainting
  • Somnolence
  • Insomnia
  • Vertigo
  • Mental confusion
  • Agitation
  • Depression
  • Hallucinations
  • Arthritic symptoms
  • Myalgic symptoms
  • Blurred vision
  • Taste disturbance
  • Peripheral edema
  • Increased sweating
  • Gynecomastia
  • Leucopenia
  • Thrombocytopenia
  • Agranulocytosis
  • Pancytopenia
  • Anaphylactic shock
  • Malaise
  • Fever
  • Bronchospasm
  • Encephalopathy
  • Hepatitis
  • Interstitial nephritis
  • Hepatic failure
  • Increases in liver enzymes

Pregnancy & Lactation

  • No adverse effects of omeprazole on pregnancy or fetus/newborn child based on epidemiological studies
  • Use during pregnancy may be considered
  • No information on passage into breast milk or effects on the neonate
  • Breastfeeding discontinuation if essential use

Precautions & Warnings

  • Avoid concomitant use with clopidogrel
  • Possibly associated with increased risk for osteoporosis-related fractures
  • Atrophic gastritis noted in patients treated long-term
  • Concomitant use with methotrexate may lead to toxicities

Therapeutic Class

Proton Pump Inhibitor

Storage Conditions

Keep in a dry place away from light and heat

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