Eupi 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (10 x 10: ৳ 500.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Pharmasia limited |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
- After discontinuation, secretory activity returns gradually over 3 to 5 days
Dosage
- Dosage for benign gastric and duodenal ulcer: 20 mg once daily for 4 weeks in duodenal ulceration, 8 weeks in gastric ulceration
- Maintenance dose for recurrent duodenal ulcer: 20 mg once daily
- Dosage for NSAID-associated duodenal or gastric ulcer: 20 mg once daily for 4 weeks, continued for further 4 weeks if not fully healed
- Dosage for gastro-esophageal reflux disease: 20 mg once daily for 4 weeks, continued for further 4-8 weeks if not fully healed
Administration
- Intravenous administration only for Omeprazole IV injection
- Omeprazole IV infusion should be given as an intravenous infusion over a period of 20-30 minutes or more
Interaction
- Reduced absorption of ketoconazole during Eupi treatment
- Delay in the elimination of diazepam, phenytoin, and warfarin
- Monitoring of patients receiving warfarin or phenytoin is recommended
- Concomitant treatment with Eupi and clarithromycin results in increased plasma concentrations
- No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, or antacids
Contraindications
- Known hypersensitivity to Omeprazole
- Possibility of malignancy in suspected gastric ulcer
Side Effects
- Skin rash, urticaria, and pruritus have been reported
- Diarrhoea and headache have been reported
- Other gastrointestinal reactions include constipation, nausea/vomiting, flatulence, and abdominal pain
- Dizziness, light headedness, and feeling faint have been associated with treatment
- Reversible mental confusion, agitation, depression, and hallucinations have occurred predominantly in severely ill patients
Pregnancy & Lactation
- Results from three prospective epidemiological studies indicate no adverse effects of Omeprazole on pregnancy or on the health of the fetus/newborn child
- Omeprazole can be used during pregnancy
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Eupi
- Observational studies suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Related Brands
- Omimak 20 mg (Capsule (Enteric Coated)) - maks-drug-limited
- Seclogen 40 mg (Capsule (Enteric Coated)) - biogen-pharmaceuticals-ltd
- Seclotil 40 mg (Capsule (Enteric Coated)) - pristine-pharmaceuticals-ltd
- Seclotil 20 mg (Capsule (Enteric Coated)) - pristine-pharmaceuticals-ltd
- Tase 20 mg (Capsule (Enteric Coated)) - union-pharmaceuticals-ltd