Vectra 8 mg (Tablet)
Unit Price: ৳ 3.00 (5 x 10: ৳ 150.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Betahistine dihydrochloride |
| Company | Healthcare pharmaceuticals ltd |
| Also available as |
Indications
- Meniere's disease
- Meniere-like syndromes
- vertigo
- tinnitus
- loss of hearing
- nausea
- vomiting
Description
- Histamine analog
- improves circulation
- relieves vertigo symptoms
- pressure reduction
- inner ear
- relieves Meniere's disease symptoms
Pharmacology
- Multifactorial mechanism of action
- disruption of endolymphatic fluid homeostasis
- histamine H1-receptor agonist
- vasodilatory effect
- reduction in endolymphatic pressure
- increase in vestibulocochlear blood flow
- histamine H3-receptor antagonist
- elevation of neurotransmitters levels
- inhibition of vestibular nuclei
Dosage & Administration
- Initial oral treatment 8-16mg three times daily
- Preferably taken with meals
- Maintenance doses 24-48 mg daily
- Dose not to exceed 48mg
- Adjustable dosage for individual patient needs
- Possible improvement after a couple of weeks of treatment
- No data for patients with hepatic impairment
- No data for patients with renal impairment
- Limited data in the elderly
- Not recommended for children and adolescents below age 18
Interaction
- No proven hazardous interactions
- Potential interactions with ethanol, pyrimethamine, dapsone, potentiation with salbutamol
Contraindications
- Contraindicated in patients with phaeochromocytoma
- Hypersensitivity to the active substance
Side Effects
- Generally well tolerated
- No known serious adverse effects
- Possible gastrointestinal disturbances, headache, rashes, pruritus
Pregnancy & Lactation
- Safety in human pregnancy not completely established
- No known teratogenic effect in animals
- Careful assessment of potential benefits during pregnancy
- Excretion in breast milk of nursing mothers
- Toxicity to the neonate at excreted concentrations not known
Precautions & Warnings
- Caution in patients with peptic ulcer or a history of peptic ulceration
- Caution in patients with bronchial asthma
- Caution in patients with urticaria, rashes, or allergic rhinitis
- Caution in patients with severe hypotension
- Avoid in patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
- Rare reports of drowsiness
- Caution while driving or operating machinery
Overdose Effects
- Nausea
- Vomiting
- Dyspepsia
- Ataxia
- Seizures
- Serious complications in cases of intentional overdose especially in combination with other overdosed drugs
- No specific antidote
- Gastric lavage and symptomatic treatment recommended
Therapeutic Class
- Drugs used in Meniere's diseases
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children