Menaril 16 mg (Tablet)
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Betahistine dihydrochloride |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Product Title
- Menaril
Category
- Medicine
- Treatment
- Pharmaceutical
Indications
- Meniere's disease
- Meniere-like syndromes
- Vertigo
- Tinnitus
- Progressive loss of hearing
- Nausea
- Vomiting
Description
- Histamine analog
- Improves circulation in the inner ear
- Reduces pressure on the membranous labyrinth
Pharmacology
- Acts as a histamine H1-receptor agonist
- Vasodilatory effect
- Increases permeability of blood vessels
- Reduces endolymphatic pressure
- Increases vestibulocochlear blood flow
- Acts as a histamine H3-receptor antagonist
- Elevates levels of neurotransmitters including serotonin
Dosage & Administration
- Initial oral treatment: 8 to 16mg three times daily
- Maintenance doses: 24-48 mg daily
- Dose not to exceed 48mg
- Dosage adjustments for individual patient needs
- Improvement may take a couple of weeks
- No data for hepatic impairment
- No data for renal impairment
- Limited data in the elderly
- Not recommended for children and adolescents below age 18
Interaction
- No proven cases of hazardous interactions
- Reported interaction with ethanol and pyrimethamine with dapsone
- Potentiation with salbutamol
- Mutual attenuation with H1 antagonists
Contraindications
- Phaeochromocytoma
- Hypersensitivity to the active substance
Side Effects
- Gastrointestinal disturbances
- Headache
- Rashes
- Pruritus
Pregnancy & Lactation
- Safety in human pregnancy not completely established
- Unknown teratogenic effect in animals
- Excreted in breast milk
- Toxicity to neonate at these concentrations is not known
Precautions & Warnings
- Caution in patients with peptic ulcer or history of peptic ulceration
- Caution in patients with bronchial asthma
- Caution in patients with urticaria, rashes, or allergic rhinitis
- Caution in patients with severe hypotension
- Not for patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption
- Rare reports of drowsiness
- Caution with activities requiring concentration
Overdose Effects
- Nausea
- Vomiting
- Dyspepsia
- Ataxia
- Seizures
- Serious complications in intentional overdose especially in combination with other drugs
- No specific antidote
- Gastric lavage and symptomatic treatment recommended
Therapeutic Class
- Drugs used in Meniere's diseases
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of reach of children