Aluric 100 mg (Tablet)
Unit Price: ৳ 4.10 (100's pack: ৳ 410.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Allopurinol |
| Company | Sonear laboratories ltd |
Indications
- Reduction of urate/uric acid formation
- Management of gouty arthritis
- Treatment of 2,8-dihydroxyadenine (2,8-DHA) renal stones
- Management of recurrent mixed calcium oxalate renal stones
Pharmacology
- Xanthine oxidase inhibitor
- Orally administered
- Reduces production of uric acid
- Approximately 90% absorbed from the GI tract
- Plasma half-life of about 1 to 2 hours
Dosage & Administration
- Adults:
- Low dosage introduction
- Recommended dosage schedules based on condition severity
- Children: Recommended dosage based on body weight
- Elderly: Usage based on satisfactory urate reduction
- Renal Impairment:
- Reduced dosage for severe renal insufficiency
- Use at longer intervals for severe renal impairment
Interaction
- 6-Mercaptopurine or Azathioprine: Adjusted dosage when used concurrently
- Vidarabine: Increased plasma half-life
- Theophylline: Monitoring required when starting or increasing therapy
- Ampicillin or Amoxicillin: Increase in frequency of skin rash reported
- Ciclosporin: Possible increase in plasma concentration during concomitant treatment
Contraindications
- Hypersensitivity to allopurinol
Side Effects
- Rashes
- Gastrointestinal disorders
- Malaise
- Headache
- Vertigo
- Drowsiness
- Visual and test disturbances
- Hypertension
- Alopecia
- Hepatotoxicity
- Neuropathy
- Gynecomastia
- Blood disorders
Pregnancy & Lactation
- Inadequate evidence of safety in human pregnancy
- Use only when no safer alternative exists
- Data on effects on breastfed baby not available
Precautions & Warnings
- Immediate withdrawal on skin rash or sensitivity
- Reduced doses for hepatic or renal impairment
- Caution in patients under treatment for hypertension or cardiac insufficiency
Overdose Effects
Reported ingestion without adverse effects, symptoms and signs of overdose, hydration and haemodialysis as necessary
Therapeutic Class
Drugs used in Gout
Storage Conditions
Below 30°C, away from light and moisture, keep out of reach of children