Bisten Plus 2.5 mg+6.25 mg (Tablet)

Unit Price: ৳ 5.00 (30's pack: ৳ 150.00)

Medicine Details

Category Details
Generic Bisoprolol fumarate hydrochlorothiazide
Company Edruc limited
Also available as
Bisten plus 5 mg tablet Bisten plus 10 mg tablet

Indications

  • Treatment of Hypertension

Pharmacology

  • Antihypertensive effects
  • Additive effects of Bisoprolol Fumarate and Hydrochlorothiazide
  • Mechanism of action of Bisoprolol Fumarate
  • Mechanism of action of Hydrochlorothiazide
  • Effect on renal tubular mechanisms

Dosage & Administration

  • Effective doses of Bisoprolol (2.5 to 40 mg)
  • Effective doses of Hydrochlorothiazide (12.5 to 50 mg)
  • Initial therapy dosage (2.5/6.25 mg tablet once daily)

Interaction

  • Potential potentiation with other antihypertensive agents
  • Contraindication with other beta-blocking agents

Contraindications

  • Contraindicated in cardiogenic shock
  • Contraindicated in overt cardiac failure
  • Contraindicated in marked sinus bradycardia
  • Contraindicated in anuria
  • Hypersensitivity to the components

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Bradycardia
  • Arrhythmia
  • Peripheral ischemia
  • Chest pain
  • Palpitations
  • Cold extremities
  • Diarrhoea
  • Constipation
  • Nausea
  • Dyspepsia
  • Rhinitis

Pregnancy & Lactation

  • Pregnancy category C
  • Use in Pregnancy only if potential benefit justifies risk
  • Small amounts detected in the milk of lactating rats

Precautions & Warnings

  • Hyperuricemia or acute gout precautions
  • Warning signs of fluid and electrolyte imbalance
  • Hypokalemia precautions
  • Gradual withdrawal of therapy
  • Observation of patients

Overdose Effects

  • Expected signs of beta-blocker overdosage
  • Signs and symptoms of thiazide diuretics overdose

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Keep below 30°C
  • Away from light & moisture

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