Cardobis Plus 5 mg+6.25 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)

Strip Price: ৳ 110.00

Medicine Details

Category	Details
Generic	Bisoprolol fumarate hydrochlorothiazide
Company	Eskayef pharmaceuticals ltd
Also available as	Cardobis plus 25 mg tablet

Indications

Treatment of Hypertension

Pharmacology

Bisoprolol Fumarate
Hydrochlorothiazide
Antihypertensive effects
Additive effects
Membrane stabilizing activities
Electrolyte reabsorption
Sodium excretion
Chloride excretion

Dosage & Administration

Dosage range of Bisoprolol
Dosage range of Hydrochlorothiazide
Once-daily doses
Initial Therapy
Replacement Therapy
Therapy Guided by Clinical Effect

Interaction

Potentiation of other antihypertensive agents
Combination with beta-blocking agents
Monitoring of catecholamine-depleting drugs
Cautious use with myocardial depressants
Increased risk of bradycardia with concomitant use of digitalis glycosides

Contraindications

Cardiogenic shock
Overt cardiac failure
Second or third degree AV block
Anuria
Hypersensitivity to components

Side Effects

Fatigue
Dizziness
Headache
Bradycardia
Arrhythmia
Peripheral ischemia
Chest pain
Palpitations
Diarrhoea
Constipation
Nausea
Dyspepsia

Pregnancy & Lactation

Pregnancy Category
Use in Nursing Mothers
Excretion in human breast milk

Precautions & Warnings

Hyperuricemia
Fluid and electrolyte imbalance
Dryness of mouth
Muscle cramps
Muscular fatigue
Hypokalemia
Observation during therapy withdrawal

Overdose Effects

Overdose signs with beta-blocker
Lethargy
Delirium
Coma
Convulsions
Respiratory arrest
Acute loss of fluid and electrolytes
Cardiovascular symptoms
Neuromuscular symptoms
Gastrointestinal symptoms
Renal symptoms
Laboratory findings

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Temperature
Light exposure
Moisture exposure
Keep out of reach of children

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