Betafix Plus 5 mg+6.25 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Bisoprolol fumarate hydrochlorothiazide
Company Healthcare pharmaceuticals ltd
Also available as
Betafix plus 25 mg tablet

Indications

  • Treatment of Hypertension

Pharmacology

  • Bisoprolol Fumarate as a β1-selective adrenoceptor blocking agent
  • Hydrochlorothiazide as a benzothiadiazine diuretic
  • Additive antihypertensive effects of the combined agents
  • Lower incidence of hypokalemia with the combination

Dosage & Administration

  • Recommended once-daily doses for Bisoprolol and Hydrochlorothiazide
  • Antihypertensive effects increase with increasing doses of either component
  • Specific initial therapy and replacement therapy guidelines
  • Dosing titration at 14-day intervals
  • Therapy guided by clinical effect

Interaction

  • Potential potentiation of other antihypertensive agents
  • Cautions when used concurrently with catecholamine-depleting drugs
  • Careful use with myocardial depressants or inhibitors of AV conduction
  • Increased risk of bradycardia with concomitant use of digitalis glycosides and beta-blockers

Contraindications

  • Patients in cardiogenic shock, overt cardiac failure, or with marked sinus bradycardia
  • Patients with second or third degree AV block
  • Patients with anuria
  • Patients with hypersensitivity to either component of the product or to other sulfonamide-derived drugs

Side Effects

  • Mild and transient side effects reported
  • List of potential side effects including fatigue, dizziness, headache, bradycardia, arrhythmia, etc.

Pregnancy & Lactation

  • Pregnancy Category C
  • Use in pregnancy only if potential benefit justifies the risk to the fetus
  • Limited information on use in nursing mothers

Precautions & Warnings

  • Potential for hyperuricemia or acute gout with thiazide diuretics
  • Warning signs or symptoms of fluid and electrolyte imbalance
  • Careful observation needed if discontinuing therapy

Overdose Effects

  • Expected signs of overdose with a beta-blocker
  • Limited data on overdose with the product
  • Potential signs and symptoms of overdose with thiazide diuretics

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Recommended storage conditions below 30°C temperature, away from light & moisture
  • Keep out of the reach of children

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