Betacor HZ 5 mg+6.25 mg (Tablet)
Unit Price: ৳ 13.00 (3 x 10: ৳ 390.00)
Strip Price: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Bisoprolol fumarate hydrochlorothiazide |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Hypertension
Pharmacology
- Additive antihypertensive effects
- Selective adrenoceptor blocking agent
- Benzothiadiazine diuretic
- Affects renal tubular mechanisms
- Increases excretion of sodium and chloride
Dosage & Administration
- Effective once-daily doses
- Antihypertensive effects increase with increasing doses
- Initial therapy with lowest dose
- Subsequent titration for maximum recommended dose
- Substitution for titrated individual components
- Therapy guided by clinical effect
Interaction
- Potentiates action of other antihypertensive agents
- Should not be combined with other beta-blocking agents
- Closely monitor patients receiving catecholamine-depleting drugs
- Caution with concurrent use of myocardial depressants or AV conduction inhibitors
- Increased risk of bradycardia with concomitant use of digitalis glycosides
Contraindications
- Cardiogenic shock
- Overt cardiac failure
- Second or third degree AV block
- Marked sinus bradycardia
- Anuria
- Hypersensitivity to either component
Side Effects
- Fatigue
- Dizziness
- Headache
- Bradycardia
- Arrhythmia
- Peripheral ischemia
- Chest pain
- Palpitations
- Cold extremities
- Claudication
- Orthostatic hypotension
- Diarrhoea
- Constipation
- Nausea
- Dyspepsia
- Rhinitis
- Pharyngitis
Pregnancy & Lactation
- Pregnancy Category C
- No adequate and well-controlled studies in pregnant women
- Use in pregnancy only if potential benefit justifies risk to fetus
- Thiazides excreted in human breast milk
- Potential for serious adverse reactions in nursing infants
Precautions & Warnings
- Hyperuricemia or acute gout
- Warning signs or symptoms of fluid and electrolyte imbalance
- Hypokalemia risk
- Gradual withdrawal of therapy
- Careful observation of patients
Overdose Effects
- Expected signs with overdose of beta-blocker
- Lethargy
- Delirium
- Coma
- Convulsions
- Respiratory arrest
- Congestive heart failure
- Bronchospasm
- Hypoglycemia
- Acute loss of fluid and electrolytes
- Signs and symptoms in various body systems
- Laboratory findings such as hypokalemia, hyponatremia, hypochloremia, alkalosis
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children