Bisoren Plus 5 mg+6.25 mg (Tablet)

Indications

Treatment of hypertension

Pharmacology

• Bisoprolol as a beta-blocker
• Hydrochlorothiazide as a diuretic

Dosage & Administration

Once-daily doses of 2.5 to 40 mg for Bisoprolol, 12.5 to 50 mg for Hydrochlorothiazide

Interaction

Potentiation with other antihypertensive agents

Contraindications

• Cardiogenic shock
• Overt cardiac failure
• AV block
• Sinus bradycardia
• Anuria
• Hypersensitivity

Side Effects

• Fatigue
• Dizziness
• Headache
• Bradycardia
• Arrhythmia
• Peripheral ischemia
• Chest pain
• Palpitations
• Diarrhea
• Nausea
• Rhinitis

Pregnancy & Lactation

• Pregnancy Category C
• Use in nursing mothers

Precautions & Warnings

• Warning signs of fluid and electrolyte imbalance
• Observation during withdrawal of therapy

Overdose Effects

• Bradycardia
• Hypotension
• Lethargy
• Delirium
• Coma
• Convulsions

Therapeutic Class

Combined antihypertensive preparations

Storage Conditions

Below 30°C, away from light & moisture, out of reach of children