Losectil 40 mg/vial (IV Injection)
40 mg vial: ৳ 90.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Eskayef pharmaceuticals ltd |
Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Acid-related dyspepsia treatment
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase enzyme system
- Onset of antisecretory effect within one hour
- Maximum effect within two hours
- Inhibition of secretion lasts up to 72 hours
- Gradual return of secretory activity after discontinuation
Dosage
- Oral dosage for various conditions
- IV injection dosage for prophylaxis of acid aspiration
- IV injection dosage for duodenal ulcer, gastric ulcer, or reflux esophagitis
Administration
- Instructions for IV injection use
- Instructions for IV infusion use
Interaction
- Decreased intragastric acidity affecting drug absorption
- Metabolism through cytochrome P450
- Effect on the absorption and elimination of other drugs
Contraindications
- Known hypersensitivity to Omeprazole
- Need to exclude possibility of malignancy before treatment
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, erythema multiforme
- Diarrhoea, headache, constipation, nausea/vomiting
- Dry mouth, stomatitis, candidiasis
- Dizziness, somnolence, reversible mental confusion
- Arthritic and myalgic symptoms
- Blurred vision, taste disturbance, peripheral oedema
- Gynaecomastia, increases in liver enzymes
Pregnancy & Lactation
- No adverse effects of Omeprazole on pregnancy or fetus/child
- Use during pregnancy considered safe
- No information available on passage into breast milk or effects on neonate
- Discontinuation of breastfeeding if essential
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted in long-term users
- Potential for methotrexate toxicities with concomitant use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Related Brands
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