Nuprazol 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Nuvista pharma ltd |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- As prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
Inhibitor of gastric acid secretion, blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system, onset of effect within one hour, maximum effect within two hours, inhibition lasts up to 72 hours, gradual return of secretory activity over 3 to 5 days after drug discontinuation
Dosage
- Oral administration for various conditions with specific doses and duration
- IV Injection for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux esophagitis, Zollinger-Ellison syndrome
Administration
- IV Injection directions for use
- IV Infusion directions for use
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolism through cytochrome P450 leading to delayed elimination of diazepam, phenytoin, and warfarin
- Plasma concentrations affected during concomitant administration with clarithromycin
Contraindications
Known hypersensitivity to omeprazole, suspicion of gastric ulcer malignancy
Side Effects
- Mild and reversible adverse reactions including skin rash, urticaria, pruritus, photosensitivity, bullous eruption, diarrhea, headache, constipation, nausea/vomiting, dizziness, somnolence, insomnia, arthritic and myalgic symptoms, visual disturbances, taste disturbance, peripheral edema, gynaecomastia, hematological reactions, anaphylactic shock, hepatic reactions
Pregnancy & Lactation
Use during pregnancy deemed safe, no information on potential effects in breast milk or on neonate
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis observed in long-term use
- Potential interaction with methotrexate
Therapeutic Class
Proton Pump Inhibitor
Storage Conditions
Keep in a dry place away from light and heat, keep out of the reach of children
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