OC-20 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 4.00 (60's pack: ৳ 240.00)
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Central pharmaceuticals ltd |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Acid-related dyspepsia treatment
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome treatment
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
- Secretory activity returns gradually over 3 to 5 days after discontinuation
Dosage
- Different dosages for various indications and patient populations
- Oral administration for benign gastric and duodenal ulcer, NSAID-associated duodenal or gastric ulcer, gastro-esophageal reflux disease, long-term management of acid reflux disease, acid-related dyspepsia, Zollinger-Ellison syndrome, Helicobacter pylori eradication regimen, and pediatric use in severe ulcerating reflux esophagitis
- Intravenous administration for prophylaxis of acid aspiration, duodenal ulcer, gastric ulcer, reflux esophagitis, and Zollinger-Ellison syndrome
Administration
- Directions for intravenous injection
- Directions for intravenous infusion
- Instructions for reconstitution and usage
Interaction
- Potential impact on the absorption of other medications
- Metabolism through cytochrome P450
- Potential interactions with ketoconazole, diazepam, phenytoin, warfarin, clarithromycin, amoxicillin, metronidazole, digoxin, and more
Contraindications
- Known hypersensitivity to omeprazole
- Caution in patients with suspected gastric ulcer to exclude the possibility of malignancy
Side Effects
- Mild and reversible adverse reactions
- Skin rash, urticaria, pruritus, photosensitivity, bullous eruption, and more
- Gastrointestinal reactions like diarrhea, nausea/vomiting, flatulence, abdominal pain
- Neurological reactions like dizziness, headache, somnolence, insomnia, vertigo, and more
- Hematological and hepatic reactions
Pregnancy & Lactation
- Results from prospective epidemiological studies
- Use during pregnancy
- Lack of information on passage into breast milk and effects on the neonate
- Discontinuation of breastfeeding if essential use is considered
Precautions & Warnings
- Avoid concomitant use with clopidogrel
- Possible association with increased risk for osteoporosis-related fractures
- Atrophic gastritis noted in patients treated long-term
- Potential for methotrexate toxicities with concomitant use
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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