Symbion 400 mcg+12 mcg (Inhalation Capsule)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Budesonide formoterol fumarate
Company Beximco pharmaceuticals ltd
Also available as
Symbion 100 mcg inhalation capsule Symbion 200 mcg inhalation capsule Symbion 80 mcg inhaler Symbion 160 mcg inhaler Symbion 100 mcg inhaler Symbion 200 mcg inhaler Symbion 400 mcg inhaler

Indications

  • Treatment of Asthma
  • Maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD)

Description

  • Combination of Formoterol Fumarate Dihydrate BP and Budesonide BP
  • Glucocorticosteroid with dose-dependent anti-inflammatory action
  • Selective β2 adrenoceptor agonist for long-acting relaxation of bronchial smooth muscle

Pharmacology

  • Budesonide exhibits potent glucocorticoid activity
  • Formoterol Fumarate Dihydrate is a long-acting, selective β2 - adrenergic agonist

Dosage

  • Recommended maintenance dose for adults and adolescents (12 years and older)
  • Usual maintenance dose for children
  • Alternative dosage regimens for the treatment of asthma with Budesonide and Formoterol combination
  • Dosage for COPD treatment in adults (40 years and older)

Administration

  • Correct and regular use of the Inhaler will prevent or lessen the severity of asthma attacks
  • Steps for effective use of Inhaler
  • Instructions for cleaning Inhaler

Interaction

  • Co-administration with strong cytochrome P450 3A4 inhibitors should be avoided
  • Co-administration with Monoamine oxidase inhibitors and tricyclic antidepressants should be with extreme caution
  • Beta-blockers should be used with caution
  • Co-administration with diuretics should be with caution

Contraindications

  • Primary treatment of status asthmaticus or other acute episodes of asthma or COPD
  • Hypersensitivity to any of the ingredients in this preparation

Side Effects

  • Adverse events associated with Formoterol Fumarate Dihydrate and Budesonide
  • Common adverse events of Formoterol Fumarate
  • Adverse events of Budesonide

Pregnancy & Lactation

  • No clinical data on exposed pregnancies are available
  • Budesonide is excreted in breast milk
  • Formoterol passes into human breast milk

Precautions & Warnings

  • Caution in patients with diabetes mellitus, thyrotoxicosis, untreated hypokalaemia, severe hypertension, severe cardiovascular disorders, glaucoma, cataract, hypercorticism
  • Paradoxical bronchospasm may occur

Use in Special Populations

  • Recommended monitoring of children's height
  • Consideration of referring the patient to a paediatric respiratory specialist

Overdose Effects

  • Effects of overdose of Formoterol
  • Symptoms reported from isolated cases of overdosage
  • Chronic excessive doses of Budesonide

Storage Conditions

  • Inhalation capsules must not be swallowed
  • Keep away from light and wet place
  • Store at or below 25°C temperature
  • Remove Inhalation capsule from the blister pack only immediately before use in the inhalation device

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