Symbion 400 mcg+12 mcg (Inhalation Capsule)
Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00
Medicine Details
Category | Details |
---|---|
Generic | Budesonide formoterol fumarate |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- Treatment of Asthma
- Maintenance treatment of Chronic Obstructive Pulmonary Disease (COPD)
Description
- Combination of Formoterol Fumarate Dihydrate BP and Budesonide BP
- Glucocorticosteroid with dose-dependent anti-inflammatory action
- Selective β2 adrenoceptor agonist for long-acting relaxation of bronchial smooth muscle
Pharmacology
- Budesonide exhibits potent glucocorticoid activity
- Formoterol Fumarate Dihydrate is a long-acting, selective β2 - adrenergic agonist
Dosage
- Recommended maintenance dose for adults and adolescents (12 years and older)
- Usual maintenance dose for children
- Alternative dosage regimens for the treatment of asthma with Budesonide and Formoterol combination
- Dosage for COPD treatment in adults (40 years and older)
Administration
- Correct and regular use of the Inhaler will prevent or lessen the severity of asthma attacks
- Steps for effective use of Inhaler
- Instructions for cleaning Inhaler
Interaction
- Co-administration with strong cytochrome P450 3A4 inhibitors should be avoided
- Co-administration with Monoamine oxidase inhibitors and tricyclic antidepressants should be with extreme caution
- Beta-blockers should be used with caution
- Co-administration with diuretics should be with caution
Contraindications
- Primary treatment of status asthmaticus or other acute episodes of asthma or COPD
- Hypersensitivity to any of the ingredients in this preparation
Side Effects
- Adverse events associated with Formoterol Fumarate Dihydrate and Budesonide
- Common adverse events of Formoterol Fumarate
- Adverse events of Budesonide
Pregnancy & Lactation
- No clinical data on exposed pregnancies are available
- Budesonide is excreted in breast milk
- Formoterol passes into human breast milk
Precautions & Warnings
- Caution in patients with diabetes mellitus, thyrotoxicosis, untreated hypokalaemia, severe hypertension, severe cardiovascular disorders, glaucoma, cataract, hypercorticism
- Paradoxical bronchospasm may occur
Use in Special Populations
- Recommended monitoring of children's height
- Consideration of referring the patient to a paediatric respiratory specialist
Overdose Effects
- Effects of overdose of Formoterol
- Symptoms reported from isolated cases of overdosage
- Chronic excessive doses of Budesonide
Storage Conditions
- Inhalation capsules must not be swallowed
- Keep away from light and wet place
- Store at or below 25°C temperature
- Remove Inhalation capsule from the blister pack only immediately before use in the inhalation device
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