Omag-DR 20 mg (Tablet (Enteric Coated))
Unit Price: ৳ 3.00 (10 x 10: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Rangs pharmaceuticals ltd |
Also available as |
Indications
- Gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer
- Prophylaxis in patients with a history of NSAID-associated duodenal and gastric ulcer
- Gastro-esophageal reflux disease
- Long-term management of acid reflux disease
- Acid-related dyspepsia
- Severe ulcerating reflux esophagitis
- Prophylaxis of acid aspiration during general anesthesia
- Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of the antisecretory effect occurs within one hour
- Maximum effect occurring within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer
- 10-20 mg daily for long-term management of acid reflux disease
- 40 mg for prophylaxis of acid aspiration
- 60 mg once daily for Zollinger-Ellison syndrome
- 20 mg twice daily for Helicobacter pylori eradication regimen
- 10-40 mg once daily for severe ulcerating reflux esophagitis
Administration
- IV injection for prophylaxis of acid aspiration
- IV infusion over a period of 20-30 minutes or more
Interaction
- Decreased intragastric acidity affecting the absorption of ketoconazole
- Metabolism through cytochrome P450 delaying the elimination of diazepam, phenytoin, and warfarin
- Plasma concentrations of Omag-DR and clarithromycin increased during concomitant administration
- No evidence of interaction with phenacetin, theophylline, caffeine, propranolol, metoprolol, cyclosporin, lidocaine, quinidine, estradiol, amoxycillin, or antacids
Contraindications
- Known hypersensitivity to Omeprazole
- Suspected gastric ulcer with possibility of malignancy
Side Effects
- Skin rash, urticaria, and pruritus
- Photosensitivity, bullous eruption, and erythema multiforme
- Diarrhoea and headache
- Constipation, nausea/vomiting, and flatulence
- Dizziness, light-headedness, and feeling faint
- Reversible mental confusion, agitation, depression, and hallucinations
- Increases in liver enzymes
Pregnancy & Lactation
- No adverse effects of Omeprazole on pregnancy or fetus/newborn child
- Use during pregnancy is indicated
- No information available on the passage of Omeprazole into breast milk or its effects on the neonate
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Omag-DR
- Increased risk for osteoporosis-related fractures with PPI therapy
- Atrophic gastritis noted occasionally in long-term treatment
- Concomitant use of PPIs with methotrexate may lead to toxicities
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
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