Vaspine 0.5%+8% (Intraspinal Injection)
4 ml ampoule: ৳ 32.00 (2 x 5: ৳ 320.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Bupivacaine hydrochloride dextrose |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Lower abdominal surgery
- Caesarean section
- Urological surgery
- Lower limb surgery
- Hip surgery
- Intrathecal anesthesia
- Surgical procedures
- Obstetrical procedures
- Motor blockade
- Analgesia
Composition
- Bupivacaine Hydrochloride USP 20 mg
- Dextrose Anhydrous USP 320 mg
Pharmacology
- Long-acting local anesthetic
- Amide type
- Rapid onset of action
- Duration of analgesia 3-5 hours
- Muscular relaxation
- Profound lower limb relaxation
- Circulatory effects
Dosage & Administration
- Spinal anesthesia dosage 2-4 ml
- Pediatric dosage recommendations
- Dose reduction for the elderly
- Dose reduction for late-stage pregnancy
Interaction
- Careful use with antiarrhythmic drugs
- Additive toxic effects
- Phenothiazines and Butyrophenones interaction
Contraindications
- Allergy or hypersensitivity to amide type local anesthetics
- Acute active diseases of the cerebrospinal system
- Spinal stenosis
- Active disease or recent trauma in the vertebral column
- Arthritis and other diseases of the vertebral column
Side Effects
- Adverse reaction profile
- Physiological effects of nerve block
- Decrease in blood pressure
- Bradycardia
- Temporary urinary retention
- Nerve trauma
- Epidural abscess
- Cerebrospinal leakage
Pregnancy & Lactation
- No specific disturbances to the reproductive process
- No increased incidence of malformations
- Dose reduction in late stages of pregnancy
- Entry into breast milk
- No risk of affecting the breast-fed child
Precautions & Warnings
- Reactivity with certain metals
- Severe local irritation
- Single-use ampoules
- Immediate use of solution after opening
- Discarded discolored solutions
Overdose Effects
- Acute emergencies associated with high plasma levels
- Unlikely acute systemic toxicity
- Peak plasma concentrations delay
- Toxic reactions in central nervous and cardiovascular systems
Therapeutic Class
- Regional anesthesia
Storage Conditions
- Temperature not exceeding 30°C
- Dry place
- Protection from light