Orthorate 400 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Calcium orotate |
| Company | Biopharma limited |
Indications
- Prevent or treat low blood calcium levels
- Used in conditions like osteoporosis, osteomalacia, rickets, latent tetany, postmenopausal osteoporosis, senile osteoporosis, juvenile osteoporosis, drug-induced osteoporosis, pregnancy and lactation, premenstrual syndrome (PMS), hypoparathyroidism, hip joint plastic surgery
- Acts against inflammatory diseases like arthritis, psoriasis, lupus, spondylitis, cardiovascular ailments, encephalitis, retinitis, phlebitis, colitis, multiple sclerosis
- Controls weight and suppresses appetite
- Reduces the effects of mood swings
- Enhances cognitive function
- Protects the heart and enhances cardiac muscle efficiency
- Potential to minimize the risk of colon cancer
Pharmacology
- Contains Calcium Orotate
- Functional amino acid chelating ligand- orotic acid
- Assists in the transport of calcium through cellular membrane structures
- Facilitates intracellular uptake of calcium, particularly in bone
- Helps in the maintenance of healthy cartilage
- Involved in the synthesis of DNA and RNA
- Ability to penetrate complex cell membranes for metabolization in cartilage
Dosage & Administration
- 400 mg dosage: 2-3 tablets recommended daily with meals or as directed by a physician
- 740 mg dosage: 1-2 tablets recommended daily with meals or as directed by a physician
Interaction
- Decreases absorption of biphosphonates, quinolone antibiotics, tetracycline antibiotics, levothyroxine, phenytoin, tiludronate disodium
- Can interact with thiazide-type diuretics, aluminum- and magnesium-containing antacids, mineral oil, stimulant laxatives, glucocorticoids
- Factors that reduce calcium absorption: thiazide-type diuretics, aluminum- and magnesium-containing antacids, mineral oil, stimulant laxatives, oral contraceptives, estrogen compounds, anti-inflammatories, corticosteroids
Contraindications
- Incomplete or infrequent bowel movements
- Kidney stone
- Kidney disease
- Increased activity of the parathyroid gland
- High amount of Calcium in urine
- High amount of Calcium in the blood
- Extreme loss of body water
Side Effects
- Bloating and swelling in the abdomen
- Loss of appetite
- Upset stomach
- Constipation
- Nausea
- Vomiting
- Unusual weight loss
- Increased thirst/urination
- Weakness
- Unusual tiredness
- Formation of kidney stones
Pregnancy & Lactation
- Women who are pregnant and breastfeeding need more calcium
- Calcium Orotate can help reduce the risk of pregnancy-related high blood pressure
Precautions & Warnings
- Allergic reactions to Orthorate
- Inactive ingredients may cause allergic reactions or other problems
- Precaution in kidney disease, kidney stones, little or no stomach acid (achlorhydria), heart disease, pancreas disease, sarcoidosis, difficulty absorbing nutrition from food (malabsorption syndrome)
Therapeutic Class
- Minerals in bone formation
- Specific mineral preparations
Storage Conditions
- Keep out of the reach of children
- Keep in a cool & dry place
- Protect from light