Omecron 20 mg (Capsule (Enteric Coated))
Unit Price: ৳ 5.00 (5 x 10: ৳ 250.00)
Strip Price: ৳ 50.00
Medicine Details
Category | Details |
---|---|
Generic | Omeprazole |
Company | Nipro jmi pharma ltd |
Also available as |
Indications
- Treatment of gastric and duodenal ulcer
- NSAID-associated duodenal and gastric ulcer treatment
- Prophylaxis in patients with a history of NSAID-associated ulcers
- Gastro-esophageal reflux disease treatment
- Long-term management of acid reflux disease
- Treatment of acid-related dyspepsia
- Severe ulcerating reflux esophagitis treatment
- Prophylaxis of acid aspiration during general anesthesia
- Treatment of Zollinger-Ellison syndrome
- Helicobacter pylori-induced peptic ulcer treatment
Pharmacology
- Inhibitor of gastric acid secretion
- Blocks hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system
- Onset of antisecretory effect occurs within one hour
- Maximum effect occurs within two hours
- Inhibition of secretion lasts up to 72 hours
Dosage
- 20 mg once daily for benign gastric and duodenal ulcer
- 40 mg daily for severe or recurrent cases
- 10-20 mg daily for prevention of relapse in duodenal ulcer
- 20 mg once daily for NSAID-associated duodenal or gastric ulcer
- 20 mg once daily for 4 weeks for gastro-esophageal reflux disease
- 40 mg once daily for refractory gastro-esophageal reflux disease
Administration
- Omeprazole IV injection for acid aspiration prophylaxis
- Omeprazole IV infusion over a period of 20-30 minutes
- Omeprazole IV infusion dissolved in saline or 5% Dextrose for infusion
Interaction
- Decreased intragastric acidity affecting ketoconazole absorption
- Metabolized through cytochrome P450 affecting elimination of diazepam, phenytoin, and warfarin
- Plasma concentrations increased during concomitant administration with clarithromycin
Contraindications
- Known hypersensitivity to Omeprazole
- Suspicion of gastric ulcer malignancy
Side Effects
- Skin rash, urticaria, pruritus
- Photosensitivity, bullous eruption, erythema multiforme
- Diarrhea, headache, constipation
- Nausea/vomiting, flatulence, abdominal pain
Pregnancy & Lactation
- No adverse effects on pregnancy or health of fetus/newborn child
- No information available on passage into breast milk or its effects on neonate
Precautions & Warnings
- Avoid concomitant use of clopidogrel and Omeprazole
- Increased risk for osteoporosis-related fractures
- Atrophic gastritis noted occasionally in long-term treatment
Therapeutic Class
- Proton Pump Inhibitor
Storage Conditions
- Keep in a dry place away from light and heat
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