Rotate 400 mg (Tablet)
Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Calcium orotate |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of low blood calcium levels
- Treatment of osteoporosis
- Treatment of osteomalacia
- Treatment of rickets
- Preventing latent tetany
- Treatment of postmenopausal osteoporosis
- Treatment of senile osteoporosis
- Treatment of juvenile osteoporosis
- Phenobarbital-induced osteoporosis treatment
- Phenytoin-induced osteoporosis treatment
- Prednisone-induced osteoporosis treatment
- Pregnancy and lactation calcium supplementation
- Premenstrual syndrome (PMS) treatment
- Hypoparathyroidism treatment
- Hip joint plastic surgery recovery
Pharmacology
- Contains Calcium Orotate
- Functional amino acid chelating ligand- orotic acid
- Assists transport of calcium through cellular membranes
- Facilitates intracellular uptake of calcium
- Aids in the maintenance of healthy cartilage
- Involvement in DNA and RNA synthesis
Dosage & Administration
- 400mg Calcium Orotate dosage recommendation: 2-3 tablets with meal or as directed
- 740mg Calcium Orotate dosage recommendation: 1-2 tablets with meal or as directed
Interaction
- Decreases absorption of biphosphonates
- Decreases absorption of quinolone antibiotics
- Decreases absorption of tetracycline antibiotics
- Interacts with levothyroxine, phenytoin, and tiludronate disodium
- Interacts with thiazide-type diuretics
- Increases risks of hypercalcemia and hypercalciuria with diuretics
- Aluminum- and magnesium-containing antacids affect urinary calcium excretion
- Mineral oil and stimulant laxatives decrease calcium absorption
- Glucocorticoids can cause calcium depletion and osteoporosis
- Oral contraceptives and estrogen compounds reduce calcium
- Anti-inflammatories deplete calcium
Contraindications
- Incomplete or infrequent bowel movements
- Kidney stone
- Kidney disease
- High activity of the parathyroid gland
- High amount of Calcium in urine
- High amount of Calcium in the blood
- Extreme loss of body water
Side Effects
- Bloating and swelling in the abdomen
- Loss of appetite
- Upset stomach
- Constipation
- Nausea
- Vomiting
- Unusual weight loss
- Increased thirst/urination
- Weakness
- Unusual tiredness
- Formation of kidney stones
Pregnancy & Lactation
- Increased calcium need during pregnancy and lactation
- Reduction of pregnancy-related high blood pressure risk
Precautions & Warnings
- Allergy precaution
- Inactive ingredient allergy precaution
- Kidney disease precaution
- Kidney stones precaution
- Achlorhydria precaution
- Heart disease precaution
- Pancreatic disease precaution
- Sarcoidosis precaution
- Malabsorption syndrome precaution
Therapeutic Class
- Minerals in bone formation
- Specific mineral preparations
Storage Conditions
- Keep out of reach of children
- Store in a cool & dry place
- Protect from light